May 23 2022



Active ingredient: atomoxetine

Although no documented significant pharmacokinetic interactions between alcohol and atomoxetine, some studies indicate that the influence of alcohol can have a disinhibiting effect greater in patients with ADHD, which already has a worse control pulse [1].

In this regard, alcohol can impair performance at the wheel of a vehicle of patients with ADHD in an additive that could alter much the driving ability, even with blood alcohol concentrations below the legal limit. [2]

other trial results showed that alcohol can have a greater detrimental effect on some aspects of performance in ADHD than in controls on driving in adults [3].

In summary, alcohol decreases impulse control in these patients regardless of drug and disrupt driving capabilities even legal blood alcohol levels.

References:

1: Weafer J, Fillmore MT, Milich R. Increased sensitivity to the disinhibiting effects of alcohol, in adults with ADHD. Exp Clin Psychopharmacol. 2009 Apr; 17 (2) :113-21. doi: 10.1037/a0015418.
2: Weafer J, Camarillo D, Fillmore MT, Milich R, Marczinski CA. Simulated driving performance of adults with ADHD: comparisons with alcohol-intoxication. Clin Exp Psychopharmacol. 2008 Jun, 16 (3) :251-63. doi: 10.1037/1064-1297.16.3.251.
3: Barkley RA, Murphy KR, O'Connell T, Anderson D, DF Connor. Effects of two doses of Alcohol on simulator driving performance in adults with attention-deficit/hyperactivity disorder. Neuropsychology. 2006 Jan, 20 (1) :77-87.