May 23 2022

Active ingredient: ibuprofen

There are no adequate and controlled studies on human interaction between ibuprofen and ethyl alcohol.

A study in 19 healthy volunteers found no statistically significant effects of ibuprofen on alcohol, both in the maximum blood concentration of this substance and the removal rate [1].

Clinical studies suggest that ibuprofen and other (naloxone, lithium, catecholamine agonists, etc.) can reduce cognitive or behavioral effects induced by ethyl alcohol, but the results of these studies have failed conveniently be replicated. [2]


1: Barron SE, Perry JR, KE Ferslew. The effect of ibuprofen on ethanol concentration and elimination rate.J Forensic Sci 1992 Mar, 37 (2) :432-5.
2: Naranjo CA, Bremner KE. Behavioural correlates of alcohol-intoxication.Addiction. 1993 Jan, 88 (1) :25-35.