May 23 2022

Active ingredient: sulfasalazine

Once ingested, only 10-15% of the administered sulfasalazine is absorbed without suffering changes in the small intestine. The rest of the drug reaches the colon where it is degraded by the intestinal flora to aminosalicylic acid and sulfapyridine, which are absorbed and metabolized.

Therefore, the food substantially do not have any influence on the extent of absorption of sulfasalazine. However, for better tolerance in the stomach, it should be taken preferably after meals.