Topical use of adapalene has not been sistematically studied in nursing mothers. There are not available clinical works on this topic. However, the risk of using adapalene by nursing mothers for breastfed babies is enough distant, given the very low absorption of adapalene across the skin.
It is advisable to avoid any contact of the baby's skin with treated zones of the nursing mother.
Warning of the manufacturer:
It is not known whether adapalene is secreted in animal or human milk. In animal studies, infant rats suckled by mother, with circulating levels of adapalene at least 300 times those demonstrated in human clinical use, were developed normally.
The use of this medicine in women during lactation should be avoided, but, if necessary, should be avoided any contact of the drug with the newborn, nor should be applied to the chest of the woman