May 27 2022




Recommendations

Clorazepate dipotassium is excreted in breast milk. The drug passes to the baby, in whom can accumulate if the mother receives repeated doses, due to its long period of activity and its slow elimination from the body of the infant.

Clorazepate body becomes mainly desmethyldiazepam, a pharmacologically active substance, which is also produced by the metabolism of diazepam. Have been reported in infants desmethyldiazepam concentrations higher than into breast milk, which is a sure sign of accumulation of the active metabolite.

There have been reports of sedation in breastfed babies whose mothers received diazepam, with a mechanism of action similar to that of clorazepate, so it is preferable to use other drugs of the same pharmacological group, especially in the case of very young infants or neonates.

Warning of the manufacturer:

Clorazepate dipotassium is excreted in breast milk. For this reason, it should not be administered to nursing women.

Updated:08.03.08