It is a drug derived from loratadine, which is a metabolite. It is considered compatible with breastfeeding.
Desloratadine reaches a low concentration in breast milk and lacks sedative and anticholinergic effects of other antihistamines, so it is unlikely to produce disorders in the baby.
A normal or even higher doses, the amount transferred of the substance to the milk is less than 0.5% of the administered to the mother. However, its combined use with pseudoephedrine may negatively affect breastfeeding.
It is known that some antihistamines may decrease prolactin secretion in women who are not breastfeeding, although the significance of this effect on nursing mothers has not been systematically established.
Warning of the manufacturer:
Desloratadine is excreted into breast milk, therefore the use of this substance is not recommended in breastfeeding women.