Fexofenadine is considered compatible with breastfeeding.
This antihistamine reaches in breast milk a low concentration (23 to 60 mcg / L). It is estimated that an exclusively breastfed infant can ingest an amount less than 0.1% of the administered dose to the mother, so it is unlikely to cause side effects in the baby. However, as in the case of other antihistamines, this substance, associated with a sympathomimetic agent, such as pseudoephedrine, could have an adverse effect on lactation.
There have been case reports of mild irritability in infants whose mothers received fexofenadine while breastfeeding.
Warning of the manufacturer:
No data are available on the content of human milk after administering fexofenadine hydrochloride. However, when terfenadine was administered to nursing mothers it was found that fexofenadine passed into breast milk. Therefore, it is not recommended to administer fexofenadine hydrochloride to nursing mothers.