May 23 2022




Recommendations

Lorazepam has a shorter elimination period that other substances of the same therapeutic group, and its concentration in breast milk is relatively low, so that in usual doses, it seems unlikely to cause adverse effects to the baby.

With the reservations imposed by the lack of sufficient studies and in light of the limited information available, it can be inferred that the dose of lorazepam that can reach the baby is probably less than 9% of the dose delivered to his mother.

Should be noted that the infant can hydrolyze lorazepam conjugated derivatives which receives from his mother, converting them into active substance, so it is important to consider not only the unconjugated fraction passing through the milk .

No adverse reactions have been reported in the infant or the nursing process, although the literature in this regard is very limited. Probably the best alternative is to switch to another well-documented drug, if necessary.

Warning of the manufacturer:

Because benzodiazepines pass into breast milk, avoid taking this medication while breastfeeding.

Updated:08.03.08