May 27 2022




Recommendations

This drug is an analogue of prostaglandin E1, a substance normally present in colostrum and breast milk.

According to available studies, misoprostol reached a low level in breast milk, so the baby could receive negligible amounts of medicine. A dose of 600 mcg administered to postpartum women passed to the infants in a proportion less than 0.1% of the dose given to the mother. Furthermore, the half life of misoprostol in milk is 1.1 hours. For these reasons, it is unlikely that the baby could suffer the adverse effects of misoprostol exposure through breast milk at commonly used doses of this medicine.

Warning of the manufacturer:

Misoprostol is excreted in breast milk, but its concentration is negligible at 5 hours after administration./p>

Updated:19.05.08