Because of the risk of damage to the cartilage of conjunction, the fluoroquinolones have not been used in children. However it appears that a possible adverse effect of this nature is a more remote possibility of what has been believed.>
It is estimated that the calcium in breast milk may prevent the absorption of moxifloxacin that could pass to the baby through breastfeeding, although there are no data from clinical studies that could corroborate this point.
It is generally considered acceptable short-term treatment with moxifloxacin, although it is preferable to use another drug with a better known profile safety. Use of topical medication is unlikely that may pose a risk to the infant.
Warning of the manufacturer:
The use of moxifloxacin during breastfeeding is contraindicated. Like other quinolones, moxifloxacin has caused injury to the cartilage of weight bearing joints of immature animals. Preclinical data indicate that moxifloxacin passes into breast milk.