May 27 2022


No data are available about clinical experience with protriptyline during breastfeeding, so that, if it is necessary to establish antidepressant treatment, it is preferable to use an alternative drug, especially if the mother is feeding a small or premature baby.

It is not wise to extrapolate data from other tricyclic antidepressants to potential adverse effects of protriptyline.

The medical literature contains a case of galactorrhea in a mother who was breastfeeding her child while taking the drug.

Warning of the manufacturer:

This medication passes into breast milk and may result in undesirable effects on the nursing infant. It is not recommended to breastfeed while being treated with this substance.