May 27 2022


Valproic acid is considered compatible with breastfeeding.

Although there have been some observations of adverse effects on infants during the administration of the drug to the mother, probably most of them are not attributable solely to it.

A case of sedation in the child of a woman who received valproic acid along with primidone was resolved at stop breastfeeding. The effect is attributed to primidone, although the former could help to raise levels of the latter.

As is known, valproic acid is potentially hepatotoxic, so that infants whose mothers are treated with this substance should be closely monitored for the possible occurrence of liver damage. It has been published a case of thrombocytopenia and petechiae, so it should be alerted about possible early signs of bleeding tendency.

Warning of the manufacturer:

The lactating women should consult their doctor before using this medication because sodium valproate passes into breast milk. Small amounts of sodium valproate pass into breast milk, therefore, treatment with valproic acid during breastfeeding not generally involves risk to the infant. Therefore not usually necessary to stop breastfeeding. However, should consult their doctor whether to keep or not breastfeeding.