Surely, low levels of zaleplon reached in breast milk and its short elimination turn into less relevant the amounts ingested by the infant, so probably this substance is compatible with breastfeeding.
At usual doses, the infant can ingest about 1 to 1.4% of the maternal dose. There are no published observations of adverse effects on the baby, but the user experience with this drug is limited.
Warning of the manufacturer:
As zaleplon is excreted in breast milk should not be given to nursing mothers.