pregabalin: What is, what is used for, dose, side effects, brands

PREGABALIN

Indications and usage
Important information
Before taking
How to use
While taking
Side effects
Brands

List of brands containing pregabalin

This page contains list of brands of authorized pharmaceutical specialties of the active principle pregabalin in the countries listed below:

[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Korea] [ Mexico] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Indications and usage ▲

Pregabalin belongs to a group of medicines used to treat epilepsy, neuropathic pain and generalized anxiety disorder (GAD).

It is not established the safety and effectiveness of pregabalin in patients under 18 years with peripheral and central neuropathic pain, epilepsy and generalized anxiety disorder.

Peripheral and central neuropathic pain:

Pregabalin is used to treat chronic pain caused by nerve damage. There are several diseases that can cause peripheral neuropathic pain, such as diabetes or shingles. This pain could be described as hot, burning, throbbing pain, shooting pain, pricking, sharp pain, cramping, aching, tingling, numbness and stinging. The peripheral and central neuropathic pain may also be associated with mood changes, sleep disturbance, fatigue, and can have an impact on physical and social functioning and quality of life of patients.

Epilepsy:

Pregabalin is used to treat certain kinds of epilepsy (partial seizures with or without secondary generalization) in adults. Your doctor will prescribe pregabalin to treat epilepsy when current treatment is not controlling properly your condition. You should take pregabalin added to current treatment. This medicine should not be administered alone; it should always be used in combination with other antiepileptic treatments.

Generalized anxiety disorder (GAD):

Pregabalin is used in the treatment of generalized anxiety disorder (GAD). Symptoms of GAD include anxiety and worries which are prolonged and excessive and difficult to control. GAD can also cause restlessness or feeling excitement or nervousness, feeling easily fatigued, having difficulty concentrating, to have mind blank, irritability, muscle tension or sleep disturbance. This is too different from stress and strains of everyday life.

Medizzine recommends consult your doctor if you are unsure (or you do not know) why you have been given pregabalin.

Other ingredients of available commercial presentations:

Each capsule contains 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg or 300 mg pregabalin. The other ingredients are lactose monohydrate, maize starch, talc, gelatin, titanium dioxide (E171), sodium lauryl sulfate, anhydrous colloidal silica, black printing ink (containing shellac, black iron oxide (E172), propylene glycol, potassium hydroxide) and water.

Warning:

The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.

Important information ▲

This medicine contains lactose. If your doctor has told you have an intolerance to sugars, contact him before taking it.

Before taking the drug ▲

Do not use pregabalin

If you are allergic (hypersensitive) to pregabalin or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.

Allergy symptoms may include:

- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

Take special care with pregabalin

Some patients treated with pregabalin have reported symptoms suggesting an allergic reaction. These symptoms include swelling of the face, lips, tongue and throat, as well as diffuse skin rashes. If you experience any of these symptoms should seek immediate medical assistance.

Pregabalin has been associated with dizziness and somnolence, which could increase the occurrence of accidental injury (falls) in elderly patients. Therefore, you should exercise caution until be familiar with the effects that can cause the drug.

Pregabalin may be associated with blurred vision and other vision changes. If you experience any change in vision, you should inform your doctor immediately.

Diabetic patients who gain weight while are taking pregabalin may need a change in their diabetes medicines.

Certain side effects, such as drowsiness, may be more frequent because patients with spinal cord injury may be taking other medications to treat their symptoms, for example, pain or spasticity (muscular stiffness), with similar side effects to those of pregabalin, increasing severity when taken together.

There have been reports of congestive heart failure in some patients treated with this drug. Most of them were elderly with cardiovascular conditions. Before starting treatment with this medicine, should tell your doctor if you have a history of heart disease.

Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.

If in doubt, consult your doctor.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.

Especially, tell your doctor:

- Before using a new medication with pregabalin you should tell your doctor.

- Pregabalin and certain medications can influence each other (interaction). When used with certain drugs, Pregabalin and certain medications can influence each other (interaction). When used with certain drugs, can increase adverse reactions of both medicines, including respiratory failure and coma..

- The degree of dizziness, sleepiness and decreased concentration may be increased if pregabalin is taken with other medicines containing:

- Oxycodone, used as analgesic.
- Lorazepam, to treat anxiety.
- Alcohol

Pregabalin can be taken with oral contraceptives.

Use with food and beverages

Pregabalin can be taken with or without food. It is advisable not to drink alcohol during treatment with pregabalin.

Consult your doctor or pharmacist before taking any medicine.

Special physiological situations

Pregnancy and lactation

Always consult your doctor or pharmacist before taking any medicine during pregnancy or lactation.

Pregabalin should not be taken during pregnancy, unless your doctor has told you. Women of childbearing age must use an effective contraception method.

See your doctor immediately if you become pregnant, you think you might be pregnant or planning to become pregnant while are taking pregabalin.

It is not recommended to breastfeed while taking pregabalin. It is not known whether this drug is excreted in breast milk.

Use in children

It is not established safety and efficacy of pregabalin in children and adolescents (under 18). Therefore, pregabalin should not be used in this age group.

Driving and using machines

Pregabalin can cause dizziness, drowsiness and impaired concentration. You should not drive, operate heavy machinery or engage in other potentially dangerous activities until you know whether this medication affects your ability to perform these activities.

Consult your doctor or pharmacist before taking any medicine.

How to use pregabalin ▲

Follow exactly instructions of use of pregabalin provided by your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.

Your doctor will determine what dose is appropriate for you. This medicine is for oral use.

Peripheral and central neuropathic pain, epilepsy and generalized anxiety disorder:

Take the number of capsules as instructed by your doctor. The dose, which has been adjusted for you and your condition, will generally be between 150 mg and 600 mg daily.

Your doctor will indicate you taking pregabalin two or three times a day. If you should take it twice a day, take it once in the morning and once in night, at about the same time every day. For three times a day, take it at morning, noon and evening, at about the same time each day.

If you are an elderly patient (over 65 years), you should take pregabalin normally, except if you have kidney problems.

Your doctor may prescribe other dosing regimen or different dose if you have kidney problems.

Swallow the capsule whole, with a little water.

Continue to take pregabalin until your doctor tells you to stop.

If you think the effect of the medicine is too strong or too weak, consult your doctor.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

While you take pregabalin ▲

If a doctor prescribes another medicine, tell you are taking pregabalin.

Check with your doctor regularly developments of disorder that motivates the use of pregabalin. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.

Do not restart treatment with pregabalin at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.

If you feel unwell during treatment with pregabalin, immediately consult your doctor.

If you take more than you should:

Consult your doctor or pharmacist immediately or call the National Poisons Information Service in your country. If you have taken an overdose of pregabalin, go to the emergency department of the nearest hospital. Take the container with you, even if it is empty.

If you forget to take pregabalin

It is important to take pregabalin regularly, at the same time each day. If you miss a dose, take it as soon as you remember unless it is near the time of the next dose. In that case, continue with the next dose as normal.

Do not take a double dose to make up for a forgotten dose.

If you stop taking pregabalin

Do not stop taking this medicine unless your doctor tells it. If you stop treatment, this should be done gradually over a minimum of one week.

Upon completion of pregabalin treatment both long and short term, you should be aware that may experience certain side effects. These include sleep problems, headache, nausea, diarrhea, flu-like symptoms, nervousness, depression, pain, sweating and dizziness.

Until now, It is unclear whether these symptoms occur more commonly or are more severe if you have been taking pregabalin for a long period of time.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Side Effects of pregabalin ▲

Like all medicines, pregabalin can cause side effects, although not everybody gets them.

The frequency of side effects is classified into:

Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data

Very common side effects (affect more than 1 in 10 patients):

- Dizziness, tiredness

Common side effects (affect 1 in 10-100 patients):

- Increased appetite
- Euphoria, confusion, changes in sexual appetite, irritability
- Disturbance in attention, clumsiness, memory impairment, tremors, slurred speech, tingling
- Blurred vision, double vision
- Vertigo
- Dry mouth, constipation, vomiting, flatulence
- Difficulty in erection (erectile dysfunction)
- Swelling of the extremities, feeling drunk, abnormal gait
- Weight gain

Uncommon side effects (affect 1 in 100-1000 patients):

- Loss of appetite
- Change in self-perception, restlessness, depression, agitation, mood changes, insomnia aggravation, difficulty finding words, hallucinations, abnormal dreams, panic attacks, apathy
- Difficulty thinking, numbness, unusual eye movement, jerky movements, reduced reflexes, hyperactivity, dizziness on standing, sensitive skin, loss of taste, burning sensation, tremor to move, decreased consciousness, fainting
- Dry eyes, swollen eyes, sore eyes, tired eyes, or runny eyes
- Increased heart rate
- Flushing, hot flushes
- Difficulty breathing, nasal dryness
- Swollen abdomen, increased saliva production, heartburn, numbness around the mouth
- Sweating, rash
- Muscle spasms, joint swelling, muscle cramps, muscle pain, joint pain, back pain, pain in limb, muscle stiffness
- Difficult or painful urination, inability to hold urine,
- Weakness, fall, thirst, chest tightness

Rare side effects (affect 1 in 1.000-10.000 patients):

- Decreased blood pressure, coldness in hands and feet, increased blood pressure
- Cough, nasal congestion
- Muscle damage
- Chest pain, cessation of menstruation
- High blood sugar level
- Increased sensitivity to noise
- Heart rhythm disturbances
- Kidney failure, reduced urine output

Have been reported other adverse effects during the post-marketing phase of the drug, including:

- Heart failure,
- Unconsciousness,
- Hypersensitivity and allergic reactions (which may include swollen face, swollen tongue (angioedema), difficulty breathing (asthma, bronchospasm), itching,
- Eye inflammation (keratitis),
- Severe skin reaction characterized by rash, blisters (Stevens-Johnson syndrome), peeling skin and pain,
- mental impairment,
- Urinary retention,
- Diarrhea, headache and nausea.

If you experience swollen face or tongue or if your skin becomes red with blistering or peeling, should seek immediate medical assistance.

Certain side effects, such as drowsiness, may be more frequent because patients with spinal cord injury may be taking other medications to treat, for example, pain or spasticity (muscular stiffness), with similar adverse effects to pregabalin so that the intensity of these effects may be increased when taken together.

This list not includes all adverse reactions associated with the use of pregabalin, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.

If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.

If any of the side effects gets serious, tell your doctor or pharmacist.

List of brands containing pregabalin ▲

This page contains list of brands of authorized pharmaceutical specialties of the active principle pregabalin in the countries listed below:

[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Korea] [ Mexico] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Warning:

With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.

Australia: ▲

APO-PREGABALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
APOTEX-PREGABALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
CHEMMART PREGABALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
GABRICA 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
GENRX PREGABALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
LYRICA 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
LYRIGALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
NEURICA 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREBALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN AN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN GH 20 mg/ml, oral solution
PREGABALIN GH 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN GPPL 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN GXP 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN LAPL 20 mg/ml, oral solution
PREGABALIN LAPL 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN LUPIN 20 mg/ml, oral solution
PREGABALIN LUPIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABALIN-CH 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
PREGABICA 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules
TERRY WHITE CHEMISTS PREGABALIN 25, 50, 75, 100, 150. 200, 225 & 300 mg, capsules

Brazil: ▲

LYRICA 75 mg, 14 & 28 capsules
LYRICA 150 mg, 14 & 28 capsules
PREGABALINA ZODIAC 75 mg, 14 & 28 capsules
PREGABALINA ZODIAC 150 mg, 14 & 28 capsules

Canada: ▲

LYRICA 25 mg, 60 capsules
LYRICA 50 mg, 60 capsules
LYRICA 75 mg, 60 capsules
LYRICA 150 mg, 60 capsules
LYRICA 225 mg, 60 capsules
LYRICA 300 mg, 60 capsules

France: ▲

LYRICA 20 mg/ml, oral solution
LYRICA 25, 50, 75, 100, 150, 200 & 300 mg, capsules

Germany: ▲

LYRICA 20 mg/ml, oral solution
LYRICA 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABADOR 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABAHEXAL 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABALIN-1 A PHARMA 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABALIN AL 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABALIN BETA 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABALIN GLENMARK 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABALIN HENNIG 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules
PREGABALIN-RATIOPHARM 25, 50, 75, 100, 150, 200, 225 & 300 mg, capsules

India: ▲

CUPREGA 75 mg, slow release tablets
FIBAGIN 75 mg, tablets
FIBAGIN 150 mg, tablets
GABAFIT 75 mg, capsules
GABAFIT 150 mg, capsules
GABANEXT 75 mg, capsules
GABANEXT 150 mg, capsules
GALINERVE 75 mg, capsules
GALINERVE 150 mg, capsules
JUBLIN 75 mg, capsules
JUBLIN 150 mg, capsules
LYRICA 75 mg, capsules
LYRICA 150 mg, capsules
MAXGALIN 50 mg, capsules
MAXGALIN 75 mg, capsules
MAXGALIN 150 mg, capsules
MAXGALIN-ER 75 mg, extended release tablets
MAXGALIN-ER 100 mg, extended release tablets
MAXGALIN-ER 150 mg, extended release tablets
MAXGALIN-ER 300 mg, extended release tablets
MYGALIN 75 mg, capsules
NEUBAGA 75 mg, capsules
NEUBAGA 150 mg, capsules
NEUGALIN 75 mg, capsules
NEUGALIN 150 mg, capsules
NEUGALIN 300 mg, capsules
NOVA 75 mg, capsules
NURAMED 75 mg, capsules
NURAMED 150 mg, capsules
PEG-SR 75 mg, solw release tablets
PEVESCA 75 mg, capsules
PEVESCA 150 mg, capsules
PREBAXE 75 mg, capsules
PREBAXE 150 mg, capsules
PREG 75 mg, capsules
PREGAB 75 mg, capsules
PREGAB 150 mg, capsules
PREGABA 50 mg, capsules
PREGABA 75 mg, capsules
PREGABA 150 mg, capsules
PREGABAL 75 mg, tablets
PREGABID 80 mg, capsules
PREGABID 75 mg, capsules
PREGABID-OD 100 mg, orodispersible tablets
PREGABID-OD 150 mg, orodispersible tablets
PREGABIN 75 mg, capsules
PREGABIN 150 mg, capsules
PREGACENT 75 mg, capsules
PREGACENT 150 mg, capsules
PREGACON 75 mg, capsules
PREGACON 150 mg, capsules
PREGALIN CAPS 75 mg, capsules
PREGALIN CAPS 100 mg, capsules
PREGALIN CAPS 150 mg, capsules
PREGANERVE 75 mg, capsules
PREGANERVE 100 mg, capsules
PREGANERVE 150 mg, capsules
PREGASTAR 75 mg, capsules
PREGASTAR 150 mg, capsules
PREGEB 75 mg, capsules
PREGEB 100 mg, capsules
PREGEB 150 mg, capsules
PREGEB-OD 150 mg, orodispersible tablets
PREGEB-OD 75 mg, orodispersible tablets
PREJUNATE 75 mg, capsules
PREJUNATE 150 mg, capsules
PRENEU 75 mg, tablets
PRENEUROLIN 75 mg, capsules
PRENEUROLIN 150 mg, capsules
PROAGE 75 mg, capsules
PROGAB 75 mg, tablets
PROGAB 150 mg, tablets
SANEURON 75 mg, capsules
ZYLIN 75 mg, capsules
ZYLIN 150 mg, capsules

Italy: ▲

LYRICA 20 mg/ml, oral solution
LYRICA 25 mg, capsules
LYRICA 50 mg, capsules
LYRICA 75 mg, capsules
LYRICA 100 mg, capsules
LYRICA 150 mg, capsules
LYRICA 200 mg, capsules
LYRICA 225 mg, capsules
LYRICA 300 mg, capsules

Japan: ▲

LYRICA 25 mg, capsules
LYRICA 75 mg, capsules
LYRICA 150 mg, capsules

Korea: ▲

ANARICA 75 & 150 mg, capsules
DAEWON PREGABALIN 75 & 150 mg, capsules
DONGKWANG PREGABALIN 75 & 150 mg, capsules
FLINDA 75 & 150 mg, capsules
FREECA 75 & 150 mg, capsules
GABANEURO 75 & 150 mg, capsules
GABARICA 75 & 150 mg, capsules
GABARIN 150 mg, capsules
GABARIVA 75, 150 & 300 mg, capsules
HYUNDAI PREGABALIN 75 & 150 mg, capsules
K-BALIN 75 & 150 mg, capsules
LALACA 75 & 150 mg, capsules
LYGALIN 75 & 150 mg, capsules
LYRICA 75, 150 & 300 mg, capsules
NEUROCOVER-PG 75 & 150 mg, capsules
NEUROPAIN 75 & 150 mg, capsules
NEWRICA 75 & 150 mg, capsules
PRADY 75 & 150 mg, capsules
PRALIN 75 & 150 mg, capsules
PREBALIN 75 & 150 mg, capsules
PREGABA 75 & 150 mg, capsules
PREGAL 75, 150 & 300 mg, capsules
PREGALIN 75 & 150 mg, capsules
PREORIN 150 & 200 mg, capsules
PREPENTIN 75 & 150 mg, capsules
PRILEPTOL 75 & 150 mg, capsules
RIBALIN 75 & 150 mg, capsules
RIKALYN 75 & 150 mg, capsules
SIRICA 75 & 150 mg, capsules
YANG PREGABALIN 75 & 150 mg, capsules

Mexico: ▲

LYRICA 75 mg, 14 & 28 capsules
LYRICA 150 mg, 14 & 28 capsules
LYRICA 300 mg, 14 & 28 capsules

Spain: ▲

LYRICA 25 mg, 56 & 100 capsules
LYRICA 75 mg, 56 & 100 capsules
LYRICA 150 mg, 56 & 100 capsules
LYRICA 300 mg, 56 & 100 capsules

Turkey: ▲

ALOND 25, 75, 150 & 300 mg, capsules
ALYSE 25, 75, 150 & 300 mg, capsules
GABADAY SR 50, 75 & 150 mg, slow release tablets
GEBBRA 25, 75, 150 & 300 mg, tablets
GERICA 75 & 150 mg, capsules
LIR 25, 75 & 150 mg, capsules
LYPRE 25, 50, 75, 100, 150 & 300 mg, capsules
LYRICA 25, 75, 150, 225 & 300 mg, capsules
NEOGABA 25, 75, 150 & 300 mg, capsules
NEURICA 25, 75, 150 & 300 mg, capsules
NORAFIT 25, 75, 100, 150, 200, 225 & 300 mg, effervescent tablets
PADEN 75, 150 & 300 mg, capsules
PAGADIN 25, 75, 150 & 300 mg, capsules
PAGAMAX 25, 75, 150 & 300 mg, capsules
PERGE 25, 75, 150 & 300 mg, capsules
PIGUS 25, 75, 150 & 300 mg, capsules
PIREPSIL 25, 50, 75, 150 & 300 mg, capsules
PRELICA 25, 75, 150 & 300 mg, capsules
REGAPEN 25, 75, 150 & 300 mg, capsules
SNAPLINE 25, 75, 150 & 300 mg, capsules
SPESICOR 25, 75, 150 & 300 mg, capsules
SYMRA 25, 75, 150 & 300 mg, capsules
ZENIXA 25, 75, 150 & 300 mg, capsules

United Kingdom: ▲

U.S.A. and Puerto Rico: ▲

LYRICA 25 mg, 15, 30, 60 & 90 capsules
LYRICA 50 mg, 15-120 capsules
LYRICA 75 mg, 30-120 capsules
LYRICA 100 mg, 30-100 capsules
LYRICA 150 mg, 30-120 capsules
LYRICA 200 mg, 60-270 capsules
LYRICA 225 mg, 90 capsules
LYRICA 300 mg, 60 & 90 capsules
LYRICA 20 mg/ml, 16 oz. solución oral
PREGABALIN SOUTHEAST MEDICAL SOLUTIONS 75 mg, 30, 60 & 90 capsules

Page updated: December 21, 2010.