August 11 2020

ESOMEPRAZOLE

List of brands containing esomeprazole   

This page contains a list of brands of authorized pharmaceutical specialties of the active principle esomeprazole in the countries listed below:

Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Korea] [ Mexico] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Indications and usage     
Esomeprazole is a type of medication from the group of the proton-pump inhibitor (PPI). It reduces the production of stomach acid.

This medicine is indicated for:

- Treatment of gastroesophageal reflux disease (GERD): acid from the stomach amounting into the esophagus producing a burning sensation in the esophagus, inflammation, and pain.
- Eradication of Helicobacter pylori, duodenal ulcer healing, and prevention of relapse of peptic ulcers associated with Helicobacter pylori, in combination with an appropriate antibacterial therapeutic regimen.
- Healing of gastric ulcers associated with NSAIDs treatment (drugs that reduce inflammation, pain, and fever, used primarily in the treatment of disorders of the muscles and joints) in patients requiring continued treatment with these drugs.
- Prevention of gastric and duodenal ulcers associated with treatment with NSAIDs in patients at risk who need continued treatment with these drugs.
- Zollinger-Ellison syndrome: a disease characterized by a large increase in gastric acid secretion.

Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given esomeprazole.

Other ingredients of available commercial presentations:

Tablets

Besides the active ingredient esomeprazole, excipients are Glycerol monostearate, hyprolose, hypromellose, magnesium stearate, methacrylic acid copolymer and ethyl acrylate, microcrystalline cellulose, synthetic paraffin, macrogol, polysorbate 80, crospovidone, sodium stearyl fumarate, sugar spheres (sucrose and corn starch without gluten), talc, triethyl citrate. Dyes: iron oxide (red-brown, yellow) (E172) and titanium dioxide (E 171).

Granules

Each sachet contains 10 mg esomeprazole. Remaining components are:

Esomeprazole granules: Glyceryl monostearate 40-55, hydroxypropyl cellulose, Hypromellose, magnesium stearate, methacrylic acid copolymer and ethyl acrylate (1: 1) 30% dispersion, Polysorbate 80, Sugar spheres (sucrose and corn starch), talc, triethyl citrate.Carrier granules: anhydrous citric (for pH adjustment) Acid, Crospovidone, glucose, hydroxypropyl cellulose, iron oxide yellow (E172) and xanthan gum

Injectable solution

Each vial contains 40 mg of esomeprazole (as sodium salt). The other ingredients (excipients) are disodium edetate and sodium hydroxide.

Warning:

The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.

Important information     

Tablets: This medicine contains sucrose. If your doctor has told you that you have an intolerance to some sugars, contact him before taking this medicine.

Granules: This dosage form contains sucrose and glucose, which are two types of sugars. Therefore, it is important to maintain a careful oral hygiene and a careful brushing regularly. If your doctor has told you that you have an intolerance to some sugars, contact him before taking it.

Before taking the drug     

Do not use esomeprazole

If you are allergic (hypersensitive) to the active substance esomeprazole, other medicines in the same group (proton-pump inhibitor, PPI) or any of the other ingredients of the medicinal product prescribed to you. If you think you may be allergic, ask your doctor.

Allergy symptoms may include:

- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

Nor take this medicine if:

If you are being treated with atazanavir (a medicine for the treatment of patients infected with HIV-1 virus).

Take special care with esomeprazole

- If you have severe liver problems. In this case, you should consult your doctor, as he may reduce your dose.
- If you have severe kidney problems. In this case, you should consult your doctor.

If you have been prescribed triple therapy for the eradication of Helicobacter pylori or you receive esomeprazole for taking it when you need, tell your doctor about any other medications with which you are being treated.

If your doctor has told you to take the tablets only when needed and your symptoms change, you must inform him.

Consult your doctor if you have suffered previously any of the above circumstances.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.

Especially if you are taking esomeprazole while any of the following medications:

- Itraconazole, ketoconazole or voriconazole (for fungal infections),
- Diazepam (for anxiety and/or insomnia),
- Phenytoin (for epilepsy),
- Citalopram, imipramine, clomipramine (for depression),
- Warfarin or other coumarin derivatives (for blood clotting),
- Cisapride (to accelerate gastric emptying) or
- Atazanavir (for treatment of patients infected with HIV-1 virus)

you should consult your doctor immediately because taking esomeprazole with any of them can modify its effect.

Consult your doctor or pharmacist before taking any medicine.

Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.

Use with food and beverages

If you have difficulty swallowing, the tablets may be dispersed in half a glass of still water. Do not use other liquids.

Granulated gastro-resistant can be taken with or without food.

Consult your doctor or pharmacist before taking any medicine.

Special physiological situations

Always consult your doctor or pharmacist before taking any medicine during pregnancy or lactation.

Pregnancy

Before taking this medication, tell your doctor if you are pregnant or trying to become pregnant. If you are pregnant, take only esomeprazole if your doctor prescribes it.

Lactation

Before taking this medication, tell your doctor if you are breast-feeding. Do not use esomeprazole if you are breast-feeding unless your doctor tells you.

Children

Do not give this medicine to children younger than 1 year or weighing less than 10 kg (<10 kg).

Driving and using machines

There is no evidence of effects on the ability to drive or operate machinery.

Consult your doctor or pharmacist before taking any medicine.

How to use esomeprazole     

Follow carefully the instructions of use of esomeprazole provided by your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.

Method of using and route of administration

Your doctor will indicate you how much medicine to take and when to take it. You can take the tablets or granules with food or on an empty stomach.

The tablets should not be chewed or crushed. Should be swallowed whole with half a glass of liquid.

For patients with difficulty swallowing, tablets can also be dispersed in half a glass of still water. Do not use other liquids. Stir until the tablets disintegrate (observe that is not formed a clear solution ). You can drink it immediately or within 30 minutes. Always stir the liquid dispersion just before drinking.

To ensure that you have taken all the medication, rinse the glass filling it halfway with water and drink it again. The solid particles contain the medication. The granules should not be chewed or crushed.

For patients who can not swallow, the tablets can be dispersed in non-carbonated water and administered through a gastric tube. It is important to carefully check the suitability of the syringe and the selected probe.

Dosage, frequency of administration and duration of treatment:

Adults and adolescents from 12 years of age

Treatment of gastroesophageal reflux disease (GERD)

The usual dose is one or two tablets of 20 mg or 40 mg esomeprazole once daily or its equivalent in granules. The duration of treatment is generally up to 4 weeks.

Your doctor may choose that you keep taking the tablets, depending on how you respond to treatment. Once completed, your doctor may tell you to continue taking a maintenance dose of esomeprazole once daily or only when needed.

Adults

Treatment for duodenal ulcer (elimination of Helicobacter pylori) and preventing relapses of ulcers (associated with Helicobacter pylori) in combination with an appropriate antibacterial therapeutic regimen:

The usual dose is 20 mg esomeprazole twice daily. Your doctor will also tell you to take the following antibiotics: amoxicillin and clarithromycin. The usual duration of treatment is one week.

Follow carefully the instructions for taking the medication and ask your doctor if you are unsure.

Therapy for the healing of gastric ulcers and prevention of gastric and duodenal ulcers associated with NSAIDs treatment:

The usual dose is 20 mg esomeprazole once daily. The duration of treatment for healing of gastric ulcers is 4 to 8 weeks.

Treatment of Zollinger-Ellison syndrome:

The usual starting dose for adults is 40 mg esomeprazole twice daily. Your doctor will adjust the dose according to your needs and also will decide how long to take this medicine.

Children

Esomeprazole should not be administered to children younger than 1 year or weighing less than 10 kg (<10 kg).

Children between 1 and 11 years old can take this medicine. The usual dose is one sachet (10 mg) or two sachets (20 mg) once daily. The dose for children is based on body weight and the doctor will decide the correct dose.

Administration of solution for injection or infusion:

This drug is administered intravenously by a health professional.

Patients who can not take oral medication may be treated intravenously with 20-40 mg esomeprazole once daily.

Patients with reflux oesophagitis should be treated with 40 mg of esomeprazole (1 vial), once a day.

Patients with reflux disease treated symptomatically should be treated with 20 mg of esomeprazole (half a vial), once a day.

For healing of gastric ulcers associated with NSAIDs treatment, the usual dose is 20 mg of esomeprazole (half a vial), once a day

For the prevention of gastric and duodenal ulcers associated with treatment with NSAIDs, risk patients should be treated with 20 mg of esomeprazole (half a vial), once a day.

Usually, the duration of intravenous therapy is short and change to oral treatment should be performed as soon as possible.

This drug can be administered by injection or intravenous infusion after reconstitution of the solution from the powder contained in the vial.

Injection

40 mg dose: The reconstituted solution should be administered as an intravenous injection for a period of at least 3 minutes.

20 mg dose: Administer half of the reconstituted solution as an intravenous injection over a period of about 3 minutes. Dispose of all unused solution.

Perfusion

40 mg dose: The reconstituted solution should be administered as an intravenous infusion for a period of 10 to 30 minutes.

20 mg dose: Administer half of the reconstituted solution as an infusion intravenously over a period of 10-30 minutes. Dispose of all unused solution.

If you think that the effect of the medicine is too strong or too weak, consult your doctor.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

While you take esomeprazole     

If you become pregnant, contact your doctor immediately.

If a doctor prescribes another medicine , tell you are taking esomeprazole.

Check with your doctor regularly developments of disorder that motivates the use of esomeprazole. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.

Do not restart treatment with esomeprazole at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.

If you feel unwell during treatment with esomeprazole, immediately consult your doctor.

If you use more medicine than you should

Consult your doctor or pharmacist immediately. In the case of an overdose or accidental ingestion, consult the Information Poison Center in your country, indicating the product and the amount ingested.

If you forget a dose:

Take the missed dose as soon as you remember, and then continue the usual dosing schedule. However,If is near the time for next dose, skip the missed dose and wait until be the time to taking it.

Do not take a double dose to make up for missed doses.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Side Effects of esomeprazole     

Like all medicines, esomeprazole can cause side effects, although not everybody gets them.

The frequency of side effects is classified into:

Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data

Tell your doctor if you notice any of the adverse reactions described in this website or in the leaflet accompanying the package.

The adverse effects are classified according to its frequency:

Common (affect 1 in 10-100 patients), uncommon (affect 1 in 100-1000 patients), rare (affect 1 in 1.000-10.000 patients) and very rare (affect less than 1 in 10.000 patients).

Common side effects:

- Nervous system disorders: headaches
- Gastrointestinal disorders: abdominal pain, constipation, diarrhea, flatulence, nausea/vomiting.

Uncommon side effects:

- Metabolism and nutrition disorders: Limb edema (swelling by fluid accumulation)
- Psychiatric disorders: Insomnia,
- Nervous system disorders: dizziness, feeling hot, tingling or numbness, drowsiness,
- Disorders of the ear and labyrinth: Vertigo,
- Gastrointestinal disorders: Dry mouth
- Hepatobiliary disorders: Increased liver enzymes
- Disorders of the skin and subcutaneous tissue: Dermatitis, itching, rash, urticaria.

Rare side effects:

- Disorders of the blood and lymphatic system: Leukopenia (low white blood cell), thrombocytopenia (decreased number of platelets)
- Immune system disorders: Hypersensitivity reactions (allergic reactions), eg, fever, swelling of face, lips, tongue and/or throat(angioedema) and anaphylactic reaction/shock,
- Metabolism and nutrition disorders: Low sodium levels
- Psychiatric disorders: Agitation, confusion, depression,
- Nervous system disorders: Altered taste,
- Eye disorders: blurred vision
- Respiratory, thoracic and mediastinal disorders: bronchospasm
- Gastrointestinal disorders: oral inflammation, gastrointestinal fungal infections
- Hepatobiliary disorders: Hepatitis which may be accompanied by jaundice (yellowing of the skin and whites of the eyes),
- Disorders of the skin and subcutaneous tissue: Hair loss, sensitivity to light
- Musculoskeletal, connective tissue, and bone disorders: Joint pain, muscle pain
- General disorders and in administration site: discomfort, increased sweating.

Very rare side effects:

- Disorders of the blood and lymphatic system: Agranulocytosis (decrease of granulocytes, leukocytes with a defensive function), pancytopenia (global decline in the number of cells in blood)
- Psychiatric disorders: aggressiveness, hallucinations,
- Hepatobiliary disorders: Liver failure, disorientation, confusion, decreased consciousness in patients with pre-existing liver disease,
- Disorders of the skin and subcutaneous tissue: Severe skin reactions (erythema multiforme, toxic epidermal necrolysis),
- Musculoskeletal, connective tissue, and bone disorders: muscle weakness,
- Renal and urinary disorders: Interstitial nephritis (kidney disorder)
- Reproductive system and breast disorders: Enlarged breasts (gynecomastia).

If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.

If any of the side effects gets serious, tell your doctor or pharmacist.

List of brands containing esomeprazole     

This page contains a list of brands of authorized pharmaceutical specialties of the active principle esomeprazole in the countries listed below:

Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Korea] [ Mexico] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Warning:

With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.

Australia:     

NEXIUM 20 mg, 30 tablets
NEXIUM 40 mg, 30 tablets

Brazil:     

NEXIUM 20 mg, 7, 14 and 28 tablets
NEXIUM 40 mg, 7, 14 and 28 tablets
NEXIUM IV 40 mg, vials of lyophilized powder for IV solution

Canada:     

APO-ESOMEPRAZOLE 20 mg, 28 and 100 tablets
APO-ESOMEPRAZOLE 40 mg, 28 and 100 tablets
ESOMEPRAZOLE PRO DOC 20 mg, 28 and 100 tablets
ESOMEPRAZOLE PRO DOC 40 mg, 28 and 100 tablets
MYLAN-ESOMEPRAZOLE 20 mg, 100 tablets
MYLAN-ESOMEPRAZOLE 40 mg, 100 tablets
NEXIUM 10 mg, 30 sachets with granules for oral suspension
NEXIUM 20 mg, 30 tablets
NEXIUM 40 mg, 30, 60 and 100 tablets

France:     

INEXIUM 10 mg, 28 sachets with granules for oral suspension
INEXIUM 20 mg, 7 tablets
INEXIUM 40 mg, 14 tablets
INEXIUM 40 mg, lyophilized powder for IV solution

Germany:     

ESOMEPRAZOL ABZ 20 mg, 15, 30, 60 and 90 tablets
ESOMEPRAZOL ABZ 40 mg, 15, 30, 60 and 90 tablets
ESOMEPRAZOL TAD 20 mg, 15, 30, 60 and 90 tablets
ESOMEPRAZOL TAD 20 mg, 15, 30, 60 and 90 tablets
ESOMEPRAZOL RATIOPHARM 20 mg, 15, 30, 60 and 90 tablets
ESOMEPRAZOL RATIOPHARM 40 mg, 15, 30, 60 and 90 tablets
NEXIUM MUPS 20 mg, 15, 30, 60 and 90 tablets
NEXIUM MUPS 20 mg, 15, 30, 60 and 90 tablets

India:     

available associated with domperidone

Italy:     

ARILIAR 20 mg, 14 capsules
ARILIAR 40 mg, 14 capsules
AXAGON 20 mg, 14 tablets
AXAGON 40 mg, 14 tablets
AXAGON 40 mg, lyophilized powder for IV solution
ESOMEPRAZOLO DOC 20 mg, 14 tablets
ESOMEPRAZOLO DOC 40 mg, 14 tablets
ESOMEPRAZOLO EG 20 mg, 14 capsules
ESOMEPRAZOLO EG 40 mg, 14 capsules
ESOMEPRAZOLO RANBAXY 20 mg, 14 tablets
ESOMEPRAZOLO RANBAXY 40 mg, 14 tablets
ESOMEPRAZOLO MYLAN 20 mg, 14 capsules
ESOMEPRAZOLO MYLAN 40 mg, 14 capsules
ESOMEPRAZOLO SANDOZ 20 mg, 14 capsules
ESOMEPRAZOLO SANDOZ 40 mg, 14 capsules
ESOMEPRAZOLO TEVA 20 mg, 14 capsules
ESOMEPRAZOLO TEVA 40 mg, 14 capsules
ESOMEPRAZOLO ZENTIVA 20 mg, 14 capsules
ESOMEPRAZOLO ZENTIVA 40 mg, 14 capsules
ESOPRAL 20 mg, 14 tablets
ESOPRAL 40 mg, 14 tablets
ESOPRAL 40 mg, lyophilized powder for IV solution
LUCEN 20 mg, 14 tablets
LUCEN 40 mg, 14 tablets
LUCEN 40 mg, lyophilized powder for IV solution
LUCEN 10 mg, 28 sachets with granules for oral suspension
NEXIUM 20 mg, 14 tablets
NEXIUM 40 mg, 14 tablets
NEXIUM 40 mg, lyophilized powder for IV solution
NEXIUM 10 mg, 28 sachets with granules for oral suspension

Japan:     

Information not available

Korea:     

NEXIUM 20 mg, tablets
NEXIUM 40 mg, tablets

Mexico:     

NEXIUM MUPS 20 mg, 14 tablets
NEXIUM MUPS 40 mg, 7 and 14 tablets
NEXIUM 2.5 mg, 7, 14 and 28 sachets
NEXIUM 5 mg, 7, 14 and 28 sachets
NEXIUM 10 mg, 7, 14 and 28 sachets
NEXIUM 20 mg, 7, 14 and 28 sachets
NEXIUM 40 mg, 7, 14 and 28 sachets
NEXIUM IV 40 mg, 1 vial for injectable solution

Spain:     

AXIAGO 20 mg, 14, 28 and 56 tablets
AXIAGO 40 mg, 14 and 28 tablets
AXIAGO 10 mg granules for oral suspension, 28 sachets
NEXIUM MUPS 20 mg, 14, 28 and 56 tablets
NEXIUM MUPS 40 mg, 14 and 28 tablets
NEXIUM 10 mg granules for oral suspension, 28 sachets
NEXIUM 40 mg, lyophilized powder, 1 and 10 vials

Turkey:     

ESMARA 20 mg, 28 tablets
ESMARA 40 mg, 28 tablets
NEXIUM 10 mg, 28 sachets with granules for oral suspension
NEXIUM 20 mg, 14 and 28 tablets
NEXIUM 40 mg, 14 and 28 tablets
NEXIUM 40 mg, lyophilized powder for IV solution
NEXOMEP 20 mg, 28 tablets
NEXOMEP 40 mg, 28 tablets
NEXSTEP 20 mg, 28 tablets
NEXSTEP 40 mg, 28 tablets

United Kingdom:     

ESOMEPRAZOLE AAH PHARMA 20 mg, 28 capsules
ESOMEPRAZOLE AAH PHARMA 20 mg, 28 tablets
ESOMEPRAZOLE AAH PHARMA 40 mg, 28 capsules
ESOMEPRAZOLE AAH PHARMA 40 mg, 28 tablets
ESOMEPRAZOLE AAH PHARMA 40 mg, lyophilized powder for IV solution
ESOMEPRAZOLE ACTAVIS 20 mg, 28 tablets
ESOMEPRAZOLE ACTAVIS 40 mg, 28 tablets
ESOMEPRAZOLE ALLIANCE 20 mg, 28 tablets
ESOMEPRAZOLE ALLIANCE 40 mg, 28 tablets
ESOMEPRAZOLE GENERICS 20 mg, 28 capsules
ESOMEPRAZOLE GENERICS 40 mg, 28 capsules
ESOMEPRAZOLE TEVA 20 mg, 28 tablets
ESOMEPRAZOLE TEVA 40 mg, 28 tablets
ESOMEPRAZOLE SUN PHARMA 40 mg, lyophilized powder for IV solution
ESOMEPRAZOLE ZENTIVA 20 mg, 28 tablets
ESOMEPRAZOLE ZENTIVA 40 mg, 28 tablets
NEXIUM 10 mg, 28 sachets with granules for oral suspension
NEXIUM 20 mg, 28 tablets
NEXIUM 40 mg, 28 tablets
NEXIUM 40 mg, lyophilized powder for IV solution

U.S.A. and Puerto Rico:     

NEXIUM 20 mg, 15, 28, 30, 60 and 90 extended release capsules
NEXIUM 40 mg, 10, 30, 60 and 90 extended release capsules
NEXIUM 10 mg, 30 sachets with extended release granules
NEXIUM 4 mg/ml, 10 vials with 5 ml of injectable solution
NEXIUM 8 mg/ml, 10 vials with 5 ml of injectable solution

Date page update: December 17, 2010.