February 26 2020

LORMETAZEPAM

List of brands containing lormetazepam   

This page contains a list of brands of authorized pharmaceutical specialties of the active principle lormetazepam in the countries listed below:

Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Indications and usage     

Lormetazepam belongs to the benzodiazepine group, medicines with sedative and hypnotic properties.

Lormetazepam is indicated for the short-term treatment of insomnia

Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given lormetazepam.

Other ingredients of available commercial presentations:

Tablets:

Each tablet contains, besides the active ingredient, lactose, corn starch, polyvinylpyrrolidone K-25 and magnesium stearate.

Oral drops:

The excipients of the solution in drops are saccharin sodium, orange flavor, lemon flavor, caramel flavor, glycerol, ethanol 95º, propylene glycol.

Warning:

The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.

Important information     

This medicine in tablets contains lactose. If your doctor has told you that you have an intolerance to some sugars, contact him before taking it.

Warning about the oral drops:

This medicine contains 8 g ethanol in 100 ml. Each ml (equivalent to 25 drops) contains 0.08 g of ethanol, which may constitute a risk in children, pregnant women, and patients with liver disease, alcoholism, epilepsy, brain damage or injuries. It can modify or potentiate the effect of other drugs.

This medicine contains glycerol as an excipient, which can be harmful in high doses. It can cause headaches, stomach upset, and diarrhea.

Before taking the drug     

Do not use lormetazepam

If you are allergic (hypersensitive) to lormetazepam, to other benzodiazepines or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.

Allergy symptoms may include:

- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

Nor you should take this medicine:

- If you have myasthenia gravis (very weak or tired muscles).
- If you have severe respiratory failure (shortness of breath or chest discomfort).
- If you have sleep apnea (stopping breathing for short periods during sleep).
- If you have a severe liver disease.

Take special care with lormetazepam

- If you have impaired hepatic or renal function.
- If you have angle-closure glaucoma.
- If your doctor has prescribed a prolonged treatment, it is recommended that you undergo regular blood tests, especially liver function tests.
- If you become pregnant during treatment, you should tell your doctor.
- Its use is not recommended in children.

Tolerance

After continuous use for a few weeks, it can be detected some degree of loss of efficacy to the hypnotic effects.

Amnesia

Benzodiazepines, including lormetazepam, can induce amnesia (memory disturbance). This occurs most often several hours after taking the drug, so to minimize this risk, patients should ensure continuously sleeping during 7-8 hours after taking the tablet.

Psychiatric and paradoxical reactions

During the treatment with benzodiazepines, including lormetazepam, the patient may suffer a worsening of a depressive disorder or the appearance of an earlier depression. They can also be masked suicide trends in depressive patients, which should be properly monitored.

Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.

If in doubt, consult your doctor.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.

Alcohol increases the sedative effect of this medication, so it is recommended to avoid excessive consumption of alcoholic beverages.

It should be noted that all benzodiazepines produce depressant effects on the central nervous system (CNS) when are co-administered with barbiturates and alcohol.

when lormetazepam is taken together other medicines that act on the brain, the combination may make you more drowsy than it should.

These drugs include:

- Drugs used to treat mental disorders (antipsychotics (neuroleptics), hypnotics, anxiolytics/sedatives, antidepressants)
- drugs used for strong pain relief (narcotic analgesics)
- Drugs used to treat seizures (antiepileptic drugs)
- Anesthetic drugs
- Barbiturates
- Drugs used for the treatment of allergies (sedative antihistamines).

Similarly, administering lormetazepam together other medicines such as clozapine, sodium valproate, probenecid, theophylline or aminophylline can alter the lormetazepam effect, prolonging or decreasing its activity.

Special physiological situations

Pregnancy and lactation:

Always consult your doctor or pharmacist before taking any medicine during pregnancy or breastfeeding.

Tell your doctor if you are or intend to become pregnant.

The use of benzodiazepines, including lormetazepam, appears to be related to a possible increased risk of congenital malformations in the first trimester of pregnancy. Benzodiazepines and its metabolites can pass from the mother to fetus through the placenta.

If, for medical reasons, the drug is administered during a late stage of pregnancy, or in high doses during labor, the neonate may suffer side effects as hypoactivity, hypothermia, hypotonia (low muscle tone), apnea (breathing difficulty), moderate respiratory depression, eating problems and imbalance in the metabolic response to cold stress.

Children born to mothers who took benzodiazepines chronically during several weeks of pregnancy or during the last period of pregnancy may have developed physical dependence and can suffer withdrawal symptoms in the postnatal period.

Lactation

Lormetazepam should not be used during lactation, as benzodiazepines are excreted in human milk. There have been cases of sedation and inability to suck in infants whose mothers were treated with benzodiazepines. These newborns should be monitored for any of its possible pharmacological effects (including sedation and irritability).

Use in children, elderly and debilitated patients:

Benzodiazepines, including lormetazepam, should not be given to children, unless absolutely necessary; the duration of treatment should be the minimum possible. The elderly and debilitated patients should receive a lower dose than adults since they are more susceptible to the drug effects.

Use in patients with respiratory failure

It is recommended using lower doses in patients with chronic respiratory insufficiency due to the risk associated with respiratory depression, such as in patients with chronic obstructive pulmonary disease (COPD).

The use of benzodiazepines, including lormetazepam, can potentially lead to fatal respiratory depression

Driving and using machines

This substance can impair the ability to drive and use machines, so you should exercise caution with this type of activity while taking this drug, as both activities require constant attention and concentration.

Consult your doctor or pharmacist before taking any medicine.

How to use lormetazepam     

Follow carefully instructions of use of lormetazepam provided by your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.

Your doctor will tell you how long your treatment with lormetazepam. Do not stop treatment early because it could not exert the desired effect.

The usual adult dose is 1 mg lormetazepam (1 tablet or 10 drops) per day, 15-30 minutes before bedtime, administered orally.

In the elderly, debilitated patients, or patients suffering cerebral vascular disorders (atherosclerosis), the dose should be reduced to ½ tablet per day (0.5 mg lormetazepam).

The usual dose may be increased at the discretion of the physician in case of serious or persistent insomnia that does not respond to the usual pattern, up to 2 tablets daily, which means a maximum of 2 mg lormetazepam.

The use of benzodiazepines may lead to physical and psychological dependence. This mainly occurs after taking the drug continuously long-term.

To prevent the most of this risk must take into account the following guidelines:

1. Take benzodiazepines only if indicated by a doctor and never should advise taking the medicine to other persons.
2. Do not increase the doses prescribed by the doctor, nor prolonging treatment longer than recommended.
3. Consult your doctor regularly to decide if you should continue treatment.
4. Treatment duration should be as short as possible.

If you stop taking lormetazepam, the symptoms that have led you to take this medicine may reappear, such as mood swings, anxiety, insomnia, restlessness, lack of concentration, headache and sweating among others, so your doctor will tell you so precisely how to decrease the dose gradually.

Do not change your dose or stop treatment without talking to your doctor.

If you think the effect of the medicine is too strong or too weak, consult your doctor.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

While you take lormetazepam     

If a doctor prescribes another medicine, tell you are taking lormetazepam.

Check with your doctor regularly developments of disorder that motivates the use of lormetazepam. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.

Do not restart treatment with lormetazepam at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.

If you feel unwell during treatment with lormetazepam, immediately consult your doctor.

If you take more than you should:

Although benzodiazepines poisoning is very rare, consult your doctor or pharmacist immediately or call the National Toxicological Information Service in your country. If you have taken an overdose of lormetazepam, go to the emergency department of the nearest hospital. Take the container with you, even if it is empty.

The symptoms of lormetazepam overdose usually are manifest by varying degrees of central nervous system depression, which can range from drowsiness to coma.

In moderate cases, symptoms include drowsiness, confusion, lethargy and dysarthria (speech disorders). In more serious cases, ataxia (incoordination of voluntary movement), paradoxical reactions.

Overdose symptoms are nausea, vomiting, low blood pressure, slowed heart rate, dizziness, drowsiness, constricted pupils, agitation, difficulty breathing or even coma.

If you forget to take lormetazepam

Do not take a double dose to make up for forgotten individual doses.

If you stop taking lormetazepam

Do not suddenly stop treatment nor do it at your own risk. Ask your doctor about how to gradually reduce the dose of lormetazepam.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Side Effects of lormetazepam     

Like all medicines, lormetazepam can cause side effects although not everybody gets them.

The frequency of side effects is classified into:

Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data

General side effects

- Common side effects: Asthenia and muscular weakness.

- Very rare side effects: Hypersensitivity and anaphylactic/anaphylactoid reactions, hyponatremia, hypothermia, Syndrome of inappropriate antidiuretic hormone (SIADH).

Cardiovascular system

- Very rare side effects: Hypotension, a decrease in blood pressure.

Digestive side effects

- Uncommon side effects: Nausea.

- Very rare side effects: Constipation, increased bilirubin, jaundice, increased liver transaminases and increased alkaline phosphatase.

Blood disorders

- Very rare side effects: Thrombocytopenia, agranulocytosis, and pancytopenia.

Nervous and sensory system disorders

- Very common side effects: Sedation, tiredness, drowsiness.

- Common side effects: Ataxia, confusion, depression, unmasking of depression, dizziness.

- Uncommon side effects: Changes in libido, impotence, decreased orgasms.

- Very rare side effects:

The effect of benzodiazepines on the CNS is dose dependent, with more severe depressive effects on the central nervous system(CNS) at high doses.

Extrapyramidal symptoms, tremor, vertigo, visual problems (including diplopia and blurred vision), dysarthria (slurred speech), headache, seizures; amnesia, disinhibition, euphoria, coma; thoughts and suicide attempts.

Paradoxical reactions such as anxiety, agitation, excitement, hostility, aggressiveness, fury, rage, sleep disturbances/insomnia, sexual desire and hallucinations.

Amnesia

Anterograde amnesia may develop when using therapeutic doses; the higher the dose the higher the risk. Amnestic effects may be associated with inappropriate behavior.

Depression

The use of benzodiazepines may unmask pre-existing depression.

Psychiatric and paradoxical reactions

When using benzodiazepines or similar compounds, reactions like restlessness, agitation, irritability, aggression, delusions, rages, nightmares, hallucinations, psychosis, inappropriate behavior and other behavioral disturbances may occur. Such reactions can be severe and appear more frequently in children and the elderly.

Dependence

Lormetazepam administration (even at therapeutic doses) may lead to the development of physical dependence: discontinuation of therapy may lead to the development of withdrawal or rebound phenomena. Psychic dependence may occur. There have been reports of drug abuse.

Respiratory system disorders

- Very rare side effects: Respiratory insufficiency, apnea, worsening of sleep apnea. This effect on the respiratory system is dose dependent, being greater at higher doses. Worsening of chronic obstructive pulmonary disease (COPD).

Cutaneous disorders

- Very rare side effects: Allergic skin reactions, alopecia.

As noted above, drug withdrawal may cause recurrence of certain symptoms due to the development of dependence.

This list does not include all adverse reactions associated with the use of lormetazepam, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.

If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.

If any of the side effects gets serious, tell your doctor or pharmacist.

List of brands containing lormetazepam     

This page contains a list of brands of authorized pharmaceutical specialties of the active principle lormetazepam in the countries listed below:

Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Warning:

With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.

Australia:     

N/A

Brazil:     

N/A

Canada:     

N/A

France:     

LORMETAZEPAM ARROW 1 mg, 14 tablets
LORMETAZEPAM ARROW 2 mg, 14 tablets
NOCTAMIDE 1 mg, 14 tablets
NOCTAMIDE 2 mg, 14 tablets

Germany:     

ERGOCALM 1 mg, tablets
ERGOCALM 2 mg, tablets
LORETAM 1 mg, capsules
LORETAM 2 mg, capsules
LORMETAZEPAM ACIS 0.5 mg, tablets
LORMETAZEPAM ACIS 1 mg, tablets
LORMETAZEPAM ACIS 2 mg, tablets
LORMETAZEPAM AL 1 mg, tablets
LORMETAZEPAM AL 2 mg, tablets
NOCTAMID 1 mg, tablets
NOCTAMID 2 mg, tablets
NOCTAMIDE 1 mg, tablets
NOCTAMIDE 1 mg, tablets
LORMETAZEPAM-TEVA 1 mg, tablets
LORMETAZEPAM-TEVA 2 mg, tablets
LORMETAZEPAM-RATIOPHARM 0,5 mg, tablets
LORMETAZEPAM-RATIOPHARM 1 mg, tablets
LORMETAZEPAM-RATIOPHARM 2 mg, tablets
SEDALAM 1 mg/5 ml, injectable solution

India:     

N/A

Italy:     

AXILIUM 2.5 mg/ml, 20 ml oral drops
IPNOLOR 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM ACTAVIS 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM ALMUS 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM ALTER 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM AUROBINDO 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM DOC GENERICI 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM EUROGENERICI 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM GERMED 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM HEXAL 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM MYLAN 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM PENSA 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM RANBAXY 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM RATIOPHARM 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM SANDOZ 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM TEVA 2.5 mg/ml, 20 ml oral drops
LORMETAZEPAM ZENTIVA 2.5 mg/ml, 20 ml oral drops
LUZUL 1 mg, 30 tablets
LUZUL 2 mg, 30 tablets
LUZUL 2.5 mg/ml, 20 ml oral drops
MEXYLOR 2.5 mg/ml, 20 ml oral drops
MINIAS 1 mg, 10 tablets
MINIAS 2 mg, 10 tablets
MINIAS 2.5 mg/ml, 20 ml oral drops

Japan:     

EVAMYL 1 mg, tablets
LORAMET 1 mg, tablets

Mexico:     

N/A

Pakistan:     

LORTEM 1 mg, tablets
LYZAPAM 1 mg, tablets
NOCTAMID 1 mg, tablets

Spain:     

ALDOSOMNIL 1 mg , 30 tablets
ALDOSOMNIL 2 mg , 20 tablets
LORAMET 1 mg, 30 tablets
LORAMET 2 mg, 20 tablets
LORMETAZEPAM CINFA 1 mg, 30 tablets
LORMETAZEPAM CINFA 2 mg, 20 tablets
LORMETAZEPAM DAVUR 1 mg, 30 tablets
LORMETAZEPAM DAVUR 2 mg, 20 tablets
LORMETAZEPAM NORMON 1 mg, 30 tablets
LORMETAZEPAM NORMON 2 mg, 20 tablets
NOCTAMID 1 mg, 30 tablets
NOCTAMID 2 mg, 20 tablets
NOCTAMID 2,5 mg/ml, 20 ml oral drops

Turkey:     

N/A

United Kingdom:     

LORMETAZEPAM AAH PHARMA 0.5 mg, 30 tablets
LORMETAZEPAM AAH PHARMA 1 mg, 30 tablets
LORMETAZEPAM ACTAVIS 0.5 mg, 30 tablets
LORMETAZEPAM ACTAVIS 1 mg, 30 tablets
LORMETAZEPAM ALLIANCE HEALTHCARE 0.5 mg, 30 tablets
LORMETAZEPAM ALLIANCE HEALTHCARE 1 mg, 30 tablets
LORMETAZEPAM ALMUS 0.5 mg, 30 tablets
LORMETAZEPAM ALMUS 1 mg, 30 tablets
LORMETAZEPAM GENERICS 0.5 mg, 30 tablets
LORMETAZEPAM GENERICS 1 mg, 30 tablets
LORMETAZEPAM GENUS PHARMA 0.5 mg, 30 tablets
LORMETAZEPAM GENUS PHARMA 1 mg, 30 tablets
LORMETAZEPAM KENT PHARMA 0.5 mg, 30 tablets
LORMETAZEPAM KENT PHARMA 1 mg, 30 tablets
LORMETAZEPAM ZENTIVA 0.5 mg, 30 tablets
LORMETAZEPAM ZENTIVA 1 mg, 30 tablets

U.S.A. and Puerto Rico:     

N/A

Page updated: December 11, 2010.