List of brands containing praziquantel
This page contains list of brands of authorized pharmaceutical specialties of the active ingredient praziquantel in the countries listed below:
[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]
Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained on the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.
The active ingredient praziquantel is an anthelmintic for oral administration, with multiple activities against various intestinal parasites, among which are:
- Cysticercosis of different location (neurocysticercosis, visceral and cutaneous cysticercosis),
- Infestations by intestinal flukes (fasciolopsiasis, heterophyiasis, metagonimiasis, and nanophyetiasis), liver (clonorchiasis, opisthorchiasis and fascioliasis) and lung (paragonimiasis),
- Schistosomiasis (Schistosoma mekongi, Schistosoma japonicum, Schistosoma mansoni and Schistosoma haematobium), given its effectiveness against all these diseases.
Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given praziquantel.
Other ingredients of available commercial presentations:
In addition to praziquantel, tablets may contain the following inactive ingredients (excipients): corn starch, silicon dioxide, magnesium stearate, microcrystalline cellulose, povidone, sodium lauryl sulfate, polyethylene glycol, titanium dioxide and hypromellose.
Warning:
The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.
Do not use praziquantel
If you are allergic (hypersensitive) to praziquantel or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.
Allergy symptoms may include:
- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).
Nor you should take this medicine:
– If you have an eye infection caused by the pork tapeworm larvae (ocular cysticercosis), since the destruction of the parasite inside the eye can lead to irreversible ocular destruction,
– If the patient is younger than four years,
- If you are receiving an enzyme-inducing drug, for example, rifampicin, which significantly reduces the level and effectiveness of praziquantel. In these cases, it is advisable to replace the antiparasitic by an alternative drug. If praziquantel is necessary, the enzyme inducer should be discontinued.
– If you have liver failure.
- Praziquantel can exacerbate neurological symptoms in patients with schistosomiasis. As a rule, This medication should not be used in people with a history of epilepsy or other signs of central nervous system damage, such as subcutaneous nodules suggestive of cysticercosis.
If this situation can be applied to you or you are not sure, tell your doctor before taking this medicine.
Take special care with praziquantel
- If you have some degree of liver failure.
- If you suffer from renal impairment you do not need a special dose adjustment,
- If you have a cardiac arrhythmia. In this case, you should be closely monitored
- In some patients have been observed elevations in liver enzymes after treatment with praziquantel.
- In all cases, to reduce gastrointestinal discomfort from praziquantel, it is recommended administering it fractionally.
Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.
If in doubt, consult your doctor.
Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.
Especially, tell your doctor or pharmacist if you are taking:
It is especially important that you tell your doctor if you are being treated with inducers or inhibitors of CYP450, as they can reduce or increase blood levels of praziquantel:
- Rifampicin (its concurrent use is contraindicated),
- Phenytoin,
- Carbamazepine,
- Cimetidine,
- Ketoconazole or itraconazole,
- Albendazole,
- Grapefruit juice,
- Erythromycin,
- Other drugs that reduce praziquantel level (dexamethasone, chloroquine).
Consult your doctor or pharmacist before taking any medicine.
Taking praziquantel with food and beverages
It is advisable to take praziquantel with meals.
Special physiological situations
Pregnancy and lactation
always consult your doctor or pharmacist before taking any medicine during pregnancy or lactation.
There are no adequate and controlled studies on the use of praziquantel in pregnant women, although in laboratory animals have been observed an increase in fetal deaths. Therefore, this drug should be used in pregnant women only if clearly needed, always under strict medical supervision.
Praziquantel passes into breast milk, reaching a concentration four times less than on the maternal plasma. For this reason, if it is necessary administering praziquantel, breastfeeding should be discontinued during the day of treatment and the following 72 hours.
Children:
It should not be used in children under 4 years.
Elderly:
Available studies suggest that elderly patients have a similar response to that of younger people.
Driving and using machines
It is not advisable driving or handling potentially dangerous machinery during the day you receive the drug and the next.
How to use praziquantel
▲Follow carefully instructions of use of praziquantel provided from your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.
Praziquantel is administered orally. The tablets should be taken with food and should be swallowed without chewing, accompanied by a sufficient amount of water. Do not hold the tablet in the mouth, since, due to its bitter taste, can cause nausea and / or vomiting.
Infestation produced by pork tapeworm, Taenia saginata, Diphyllobothrium latum, and Diphyllobothrium pacificum: 10 mg/kg body weight, in a single-day treatment.
Hymenolepis nana infestation (hymenolepiasis): 25 mg/kg body weight, in a single-day treatment.
Schistosomiasis: 20 mg/kg body weight three times daily for one day alone, administered at intervals of 4-6 hours. Alternatively, it may be administered a single dose of 40 mg/kg. The doctor will assess the possibility of repeating the treatment once or more times at intervals of 6-12 months, depending on the risk of reinfestation.
Clonorchiasis and opisthorchiasis: 25 mg/kg three times daily for one day alone, administered at intervals of 4-6 hours.
Paragonimiasis: 25 mg/kg three times a day at intervals of 4-6 hours for 2 days.
Intestinal infestations by trematodes (fasciolopsiasis, heterophyiasis, metagonimiasis and nanofietiasis): 25 mg/kg three times daily for one day alone, at intervals of 4 to 6 hours or a 40 mg/kg single dose.
Neurocysticercosis: a 50 mg/kg daily dose in 3 divided doses for 15 days or 75 mg/kg divided into three doses given at intervals of two hours, followed by 10 mg dexamethasone intramuscularly four hours after the last dose, which will repeat the 2nd and 3rd day.
Patients suffering neurocysticercosis may have a fever, nausea, vomiting, meningitis and increased intracranial pressure after completing treatment with praziquantel. These symptoms are due to the destruction of cysticerci. The doctor will assess the appropriateness of prescribing steroids to reduce or prevent these symptoms.
Visceral or cutaneous cysticercosis: 50 mg/kg divided into three doses (every 8 hours) for at least two weeks.
Children under 4 years:
Praziquantel is not recommended for children under 4 years.
Patients with hepatic impairment:
Patients with moderate or severe hepatic impairment may have diminished removal capacity praziquantel, leading to a rise in the plasma level of the drug.
If you think the effect of the medicine is too strong or too weak, consult your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
While you take praziquantel
▲If a doctor prescribes another medicine, tell you are taking praziquantel.
Check with your doctor regularly developments of disorder that motivates the use of praziquantel. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.
Do not restart treatment with praziquantel at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.
If you feel unwell during treatment with praziquantel, immediately consult your doctor.
If you take more than you should:
If you take more praziquantel that you should, or if someone else has taken your medicine, consult your doctor or pharmacist immediately or call the National Poisons Information Service in your country. If you have taken a praziquantel overdose, go to the emergency department of the nearest hospital. Take the container with you, even if it is empty.
If you forget to take praziquantel
Take the medicine as soon as you remember. However, if the time of the next dose is very close, it is appropriate to wait for the next dose. Be sure to tell your doctor the incident, as he could consider desirable to modify the dosage.
Do not take a double dose to make up for missed doses.
If you stop taking praziquantel
Do not stop treatment without the knowledge and approval of your doctor. You may experience a worsening of parasitosis.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Side Effects of praziquantel
▲Like all medicines, praziquantel can cause side effects although not everybody gets them.
The frequency of side effects is classified into:
Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data
Generally, praziquantel is well tolerated. Side effects are generally mild and transient, not requiring treatment.
Have been observed the following side effects:
- General discomfort,
- Headache,
- Dizziness, vertigo,
- Abdominal pain with or without nausea,
- Temperature increase,
- Rarely, urticaria.
These symptoms may be due to the infestation itself. Side effects may be more frequent and/or severe in patients with high parasite load.
Other side effects:
The side effects observed after the marketing authorization include:
- Abdominal pain, bloody diarrhea, vomiting
- Generalized allergic reactions, including polyserositis, itching (pruritus),
- Decrease or loss of appetite,
- Arrhythmias including bradycardia, ectopic beats, ventricular fibrillation and atrioventricular block,
- Asthenia, fatigue, tiredness,
- Drowsiness,
- Seizures,
- Increased number of eosinophils in the blood (eosinophilia),
- muscle aches (myalgia),
- Hyperglycemia (increased blood sugar) in patients with neurocysticercosis.
This list does not include all adverse reactions associated with the use of praziquantel, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.
If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.
If any of the side effects gets serious, tell your doctor or pharmacist.
List of brands containing praziquantel
▲This page contains list of brands of authorized pharmaceutical specialties of the active principle praziquantel in the countries listed below:
[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]
Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained on the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.
Warning:
With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.
Australia: ▲
BILTRICIDE 600 mg, 8 tablets
Brazil: ▲
CESTOX 150 mg, 12 tablets
CISTICID 500 mg, 50 tablets
Canada: ▲
BILTRICIDE 600 mg, 6 tablets
France: ▲
BILTRICIDE 600 mg, 6 tablets
Germany: ▲
BILTRICIDE 600 mg, 6 tablets
CESOL 150 mg, 6 tablets
CYSTICIDE 500 mg, 90 tablets
India: ▲
CEST 600 mg, tablets
CYSTICIDE 600 mg, tablets
DISTOCIDE 600 mg, tablets
PRAZINE 600 mg, tablets
Italy: ▲
N/A
Japan: ▲
BILTRICIDE 600 mg, 6 tablets
Mexico: ▲
CESOL 150 mg, 4 tablets
CISTICID 600 mg, 25 & 75 tablets
Pakistan: ▲
N/A
Spain: ▲
N/A
Turkey: ▲
N/A
United Kingdom: ▲
N/A
U.S.A. and Puerto Rico: ▲
BILTRICIDE 600 mg, 6 tablets
Page updated: October 06, 2010.