Risk level in pregnancy: This medicine is classified as Category C.
Acetazolamide, both oral and injectable administration caused limb defects in laboratory animals (mice, rats, hamsters and rabbits). There are no controlled studies in pregnant women.
Meaning of category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.