May 22 2022

Classification of the active ingredient Hydrocortisone

Risk level in pregnancy: This medicine is classified as Category C.

Corticosteroids are teratogenic in laboratory animals when administered systemically, even at low doses.

The derivatives of this group with greater power may also lead to injury when applied locally. This, coupled with the lack of clinical studies to support its use make it advisable not to use hydrocortisone or other similar active ingredients more than when strictly necessary and the expected benefits outweigh the possible risks. In any case, never is recommended using local corticosteroids at high doses or for long periods of time.

Update 18.07.2009

Meaning of category C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.