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Adverse reactions to Acyclovir

  • 1. Acute colitis

    • Very rare.. Case report:Aliment Pharmacol Ther. 1997 Apr;11(2):415-7.

  • 2. Acute renal failure

    • Very rare.. Case report: Clin Nephrol. 1991 Sep;36(3):155-6. Arch Fr Pediatr. 1992 Aug-Sep;49(7):641-3.Ann Pharmacother. 1994 Apr;28(4):460-3.

  • 3. Arterial hypotension

    • Rare. Associated with bradycardia.. Case report: Schweiz Rundsch Med Prax. 1998 Nov 19;87(47):1614-8. Abstract.

  • 4. Blood creatinine increased

    • Rare.. Transient. In IV administration

  • 5. Bradycardia

    • Rare. Associated hypotension.. Case report: Schweiz Rundsch Med Prax. 1998 Nov 19;87(47):1614-8. Abstract.

  • 6. Chronic renal failure

    • Very rare.. Case report: Scand J Infect Dis. 2003;35(10):770-2.

  • 7. Coma

    • Very rare.. Case report:Anaesth Intensive Care. 2000 Jun;28(3):305-7. Chest. 1997 Aug;112(2):538-40.

  • 8. Contact dermatitis

    • Very rare.. Case report:Contact Dermatitis. 2003 Sep;49(3):155-7. Contact Dermatitis. 1990 Nov;23(5):372-3.

  • 9. Crystalluria

    • Very rare.. Case report: Arch Pathol Lab Med. 2002 Jun;126(6):753-4.

  • 10. Cutaneous necrosis

    • Very rare. Transient.. Case report:Therapie. 1987 Mar-Apr;42(2):249.

  • 11. Delirium

    • Very rare.. Case report:Clin Infect Dis. 1995 Aug;21(2):435-6.

  • 12. Depression

    • Rare.. Case report: Drug Intell Clin Pharm. 1988 Apr;22(4):306-8.

  • 13. Diarrhea

    • Frequent.

  • 14. Disorientation

    • Rare.. Case report:J Infect. 2003 May;46(4):286.Rev Clin Esp. 1997 Apr;197(4):297.

  • 15. Encephalopathy

    • Rare.. Usually associated with renal failure

  • 16. Erythroblastopenia

    • Rare.. Case report:Turk J Pediatr. 1989 Oct-Dec;31(4):317-21.

  • 17. Eye pain

    • Rare.

  • 18. Fever

    • Very rare.. Case report:Seizure. 1999 May;8(3):187-8.

  • 19. Fixed erythema

    • Very rare.. Case report:Contact Dermatitis. 1997 Apr;36(4):225.

  • 20. Hallucinations

    • Very rare. The neurotoxic symptoms of acyclovir should be distinguished from viral encephalopathy that motivates their application... Case report: J Intern Med. 1993 Nov;234(5):507-11.

  • 21. Headache

    • Common, especially in prolonged use (> 6 months).

  • 22. Hemiparesis

    • Very rare. Transient.. Case report: Ann Intern Med. 1983 Jun;98(6):921-5.

  • 23. Hepatic enzymes increased

    • Rare.

  • 24. Interstitial nephritis

    • Rare.. Case report:Nephron. 1990;56(4):436-8.

  • 25. Keratoconjunctivitis

    • Rare.

  • 26. Lacrimal obstruction

    • Rare. In topical application.. Case report: Gaoxiong Yi Xue Ke Xue Za Zhi. 1989 Aug;5(8):416-29. Abstract.

  • 27. Lethargy

    • Rare.. Case report:Hinyokika Kiyo. 1993 May;39(5):459-61.(abstract). Nephron. 1992;62(3):280-3. Clin Infect Dis. 1996 Jan;22(1):187-8. Schweiz Med Wochenschr. 1990 Aug 18;120(33):1200-3.

  • 28. Leukopenia

    • Rare.. Case report:Turk J Pediatr. 1989 Oct-Dec;31(4):317-21.

  • 29. Manic crises

    • Very rare.. Case report:Nephron. 1994;67(4):494.

  • 30. Mental confusion

    • Very rare.. Case report:Hinyokika Kiyo. 1993 May;39(5):459-61.(abstract). Nephron. 1992;62(3):280-3. Clin Infect Dis. 1996 Jan;22(1):187-8.

  • 31. Myoclonic encephalopathy

    • Very rare.. Case report:Nephrologie. 1991;12(5):241-3.

  • 32. Neutropenia

    • Very rare.. Case report:Clin Pharm. 1988 May;7(5):398-401.Clin Infect Dis. 1995 Jun;20(6):1557-9.

  • 33. Pain at the point of application

    • Rare.. Parenterally

  • 34. Papillary conjunctivitis

    • Rare. In topical application.. Case report: Gaoxiong Yi Xue Ke Xue Za Zhi. 1989 Aug;5(8):416-29. Abstract.

  • 35. Paranoid syndrome

    • Very rare.. Case report: Drug Intell Clin Pharm. 1988 Apr;22(4):306-8.

  • 36. Phlebitis

    • Frequent.. In intravenous application

  • 37. Photosensitivity

    • Very rare. Topical Application... Case report: Ann Dermatol Venereol. 2001 Feb;128(2):184.

  • 38. Posterior leukoencephalopathy

    • Very rare.. Case report: J Neurol Neurosurg Psychiatry. 2005 Sep;76(9):1308-9.

  • 39. Psychomotor agitation

    • Rare.. Case report:Ann Intern Med. 1983 Jun;98(6):921-5.

  • 40. Pulmonary infiltrate

    • Rare. Associated with pleurisy... Case report:Chest. 1990 Sep;98(3):754-6.

  • 41. Punctate keratitis

    • Frequent. In topical application.. Case report:Curr Eye Res. 1987 Jan;6(1):231-5. Gaoxiong Yi Xue Ke Xue Za Zhi. 1989 Aug;5(8):416-29. Abstract.

  • 42. Rash at the application point

    • Rare. Parenteral application... Case report: Ann Dermatol Venereol. 2000 May;127(5):496-8.

  • 43. Seizures

    • Very rare.. Case report: Bone Marrow Transplant. 1997 May;19(10):1049-51.

  • 44. Sickness

    • Frequent.

  • 45. Skin rash

    • Rare.. For parenteral application, locally.

  • 46. Stevens-Johnson syndrome

    • Very rare.. Case report: Clin Infect Dis. 1995 Oct;21(4):1038-9.

  • 47. Thrombocytopenia

    • Rare.. Case report:Am J Emerg Med. 1998 Jul;16(4):396-8.

  • 48. Tremor

    • Very rare. Intravenously... Case report: Ann Intern Med. 1983 Jun;98(6):921-5.

  • 49. Ulcerative colitis

    • Very rare.. Case report: J Dermatol. 1996 Sep;23(9):631-4.

  • 50. Vomit

    • Frequent.

  • 51. Vulvovaginitis

    • Rare.. In local application