May 22 2022

Adverse reactions to Amikacin

  • 1. Anemia
  • Very rare.

  • 2. Anosmia
  • Very rare. reversible.. Case report: Arch Otolaryngol Head Neck Surg. 2003 Dec;129(12):1331-3.

  • 3. Apnea
  • Very rare. An infant on dialysis treated with the drug.. Case report: Pediatr Nephrol. 2000 Apr;14(4):357.

  • 4. Arthralgia
  • Very rare.

  • 5. Blood magnesium decreased
  • Frequent.. References:Drug Saf. 2005;28(9):763-88. Nephrol Dial Transplant. 2000 Jun;15(6):822-6.

  • 6. Cochlear damage
  • Very rare.. References: Otol Neurotol. 2001 Jan;22(1):70-5. Acta Otolaryngol. 1990 May-Jun;109(5-6):345-52. J Intern Med. 1993 May;233(5):401-7.

  • 7. Cutaneous necrosis
  • Subcutaneous injection.. References:Presse Med. 1993 Oct 2;22(29):1366.

  • 8. Deafness
  • Very rare. Sensorineural and irreversible.. References: Pharmacotherapy. 2002 Jan;22(1):105-8. J Antimicrob Chemother. 1992 Apr;29(4):463-4. J Infect Dis. 1984 Jan;149(1):23-30.

  • 9. Eosinophilia
  • Very rare.

  • 10. Fever
  • Very rare.

  • 11. Headache
  • Very rare.

  • 12. Hematuria
  • Rare.. Increased incidence in prolonged treatment and / or renal failure and / or high-dose

  • 13. Hypercalciuria
  • By blocking calcium tubular reabsorption... Reference: J Pediatr Hematol Oncol. 1996 Feb;18(1):86-9.

  • 14. Hypocalcemia
  • Very rare. It may be associated with hypokalemia, hypomagnesemia, hypoalbuminemia, hypophosphatemia and hypoparathyroidism... Class effect. Case report: Cancer. 1977 Apr; 39 (4) :1410-4.

  • 15. Hypokalemia
  • Very rare.. Case report: Acta Clin Belg. 1996;51(5):357-9.

  • 16. Increased renal excretion of magnesium
  • By blocking tubular reabsorption of magnesium... Reference: J Pediatr Hematol Oncol. 1996 Feb;18(1):86-9.

  • 17. Macular infarction
  • Very rare. intravitreal In use.. Case report: Br J Ophthalmol. 2002 Mar;86(3):359-60.

  • 18. Macular toxicity
  • Muy rara. En aplicaci?n intrav?trea.. Case report: Klin Monatsbl Augenheilkd. 2006 May;223(5):456-8.

  • 19. Muscular hypotonia
  • Very rare. A patient undergoing ambulatory peritoneal dialysis.. Case report: Adv Perit Dial. 2006;22:69-72.

  • 20. Neuromuscular blockade
  • Very rare. Class effect.. Risk of enhancing the effect of d-tubocurarine and succinylcholine. References: Tohoku J Exp Med 1978 May, 125 (1) :71-5. Abstract.

  • 21. Oliguria
  • Rarely, related to prolonged treatment, high doses and renal insufficiency.

  • 22. Pain at the point of application
  • Rare.. In intramuscular administration

  • 23. Paresthesias
  • Very rare.

  • 24. Preretinal hemorrhage
  • Very rare. A case of multiple hemorrhages of the posterior pole of the eye after intravitreal amikacin application.. Case report: Aust N Z J Ophthalmol. 1999 Dec;27(6):435-6.

  • 25. Proteinuria
  • Rare.. Increased incidence in prolonged treatment and / or renal failure and / or high-dose

  • 26. Renal failure
  • Rare. Nephrotoxicity due to prolonged treatment doses, prior administration of other aminoglycosides and number of daily injections.. Reference: Antimicrob Agents Chemother. 2003 Mar;47(3):1010-6.

  • 27. Sickness
  • Very rare.

  • 28. Skin rash
  • Very rare.

  • 29. Tremor
  • Very rare.

  • 30. Vertigo
  • Rare.

  • 31. Vestibular Syndrome
  • Very rare. irreversible.. References: Acta Otolaryngol Suppl. 1981;383:1-19.

  • 32. Vomit
  • Very rare.