Adverse reactions to Azathioprine

• 1. Acute leukemia

Case report.

• 2. Acute pancreatitis

Rare.

• 3. Acute renal failure

Case report.. No well-established relationship

• 4. Adenocarcinoma

No well-established relationship.

• 5. Agranulocytosis

Infrequent.

• 6. Alopecia

Rare.

• 7. Anaphylactic shock

Case report.

• 8. Anemia

Frequent.

• 9. Anorexia

Frequent.

• 10. Aplastic anemia

No well-established relationship.

• 11. Arterial hypotension

Rare.

• 12. Aseptic meningitis

No well-established relationship.

• 13. Atrial fibrillation

No well-established relationship.

• 14. Azoospermia

No well-established relationship.. Case report

• 15. Budd-Chiari syndrome

No well-established relationship.

• 16. Cholestasis

Very rare.

• 17. Cholestatic hepatitis

Very rare.

• 18. Colitis

Rare.

• 19. Cytolytic hepatitis

No well-established relationship.

• 20. Diarrhea


• 21. Diverticulitis

Rare.

• 22. Erythroblastopenia

No well-established relationship.. Case report

• 23. Fever

Frequent.

• 24. Gastrointestinal perforation

Rare.. In patients with inflammatory bowel disease

• 25. Hemoptysis

Case report.. No well-established relationship

• 26. Hypersensitivity reactions

Mechanism other than type I (anaphylaxis).. No well-established relationship

• 27. Hyperuricemia

Rare.

• 28. Increased alkaline phosphatase

Very rare.

• 29. Increased blood amylase

Rare.

• 30. Interstitial nephritis

Case report.. No well-established relationship

• 31. Interstitial pneumonitis

Rare.

• 32. Jaundice

Very rare.

• 33. Joint pain

Rare.

• 34. Leukopenia

Frequent.

• 35. Liver cancer

No well-established relationship.

• 36. Liver toxicity

Infrequent.

• 37. Male sterility

Rare.. Reversible

• 38. Medular aplasia

Very rare.. Often associated with thiopurine methyltransferase deficiency

• 39. Megaloblastic anemia

No well-established relationship.

• 40. Melanoma

No well-established relationship.. Case report

• 41. Mixed hepatitis


• 42. Muscle pain

Rare.

• 43. Nodular regenerative hyperplasia of the liver

No well-established relationship.

• 44. Non-Hodgkin lymphoma

Associated with renal transplant.. Very rare

• 45. Pancytopenia

Rare.

• 46. Peripheral neuropathy

No well-established relationship.. Case report

• 47. Portal hypertension

No well-established relationship.. Case report

• 48. Respiratory insufficiency

Case report.. No well-established relationship

• 49. Reticulosarcoma

No well-established relationship.. Case report

• 50. Rhabdomyolysis

Case report.

• 51. Sickness

Frequent.. Taking the medication after meals

• 52. Skin rash

Rare.

• 53. Susceptibility to infection

Viral, fungal and bacterial.. Frequent

• 54. Thrombocytopenia

Frequent.

• 55. Vasculitis

Rare.. Often associated with other manifestations of hypersensitivity

• 56. Vomit

Frequent.