Adverse reactions to Metformin

• 1. Abdominal pain

Frequent.

• 2. Altered taste

Frequent.

• 3. Anorexia

Frequent.

• 4. Diarrhea

Frequent.

• 5. Erythema

Infrequent.

• 6. Fatigue, weakness

Very rare.

• 7. Hemolytic anemia

Case report.

• 8. Hepatic enzymes increased

Infrequent.

• 9. Hepatitis

Infrequent.

• 10. Interference with the ability to drive or operate machinery

The diabetic patient may present crisis hypoglycemia, unrelated to this medication, but are more likely if the metformin is associated with other antidiabetic agents..

• 11. Lactic acidosis

Very rare.. Usually associated with kidney failure

• 12. Megaloblastic anemia

Very rare.. Associated with malabsorption of vitamin B ₁₂

• 13. Muscular cramps

Very rare.

• 14. Pruritus

Infrequent.

• 15. Sickness

Frequent.

• 16. Steatorrhea

Very rare.

• 17. Urticaria

Infrequent.

• 18. Vitamin B12 deficiency

Very rare.. By decreasing the absorption of vitamin B ₁₂

• 19. Vomit

Frequent.