Adverse reactions to Tranexamic acid

• 1. Abdominal pain

Infrequent.

• 2. Acute renal failure

Rare. transient.. Case report:Neth J Med. 1991 Aug;39(1-2):127-8. Nephron. 1995;69(4):478-9.

• 3. Anaphylactic shock

Very rare. A case in a 72 year old patient during coronary bypass surgery... Case report: Ann Fr Anesth Reanim. 2004 Jun;23(6):607-9.

• 4. Cerebral thrombosis

Very rare. A case of fatal course of the internal carotid thrombosis after being treated for genital bleeding IUD in a 26 year old previously healthy... Case report: Br J Obstet Gynaecol. 1982 Aug;89(8):681-2.

• 5. Deep vein thrombosis

Very rare. Cases associated with ITP (idiopathic thrombocytopenic purpura).. Case report: JAMA. 1988 Jun 24;259(24):3561-2. Rinsho Ketsueki. 1988 Feb;29(2):186-8. (s?lo reference).

• 6. Diarrhea

Infrequent.

• 7. Fixed erythema

Rare.. Case report: Br J Dermatol. 1993 Feb;128(2):229-30.

• 8. Myocardial Infarction

Very rare.. Case report: Int J Cardiol. 2002 Jun;83(3):267-8.Cardiovasc Drugs Ther. 2004 May;18(3):239-40.

• 9. Myoclonus

Very rare. A case reported in a patient with advanced renal failure... Case report: J Neurol Neurosurg Psychiatry. 2003 Apr;74(4):547.

• 10. Pulmonary embolism

Very rare. A case in a patient with severe acquired haemophilia... Case report: Eur J Haematol. 2002 May;68(5):307-9.

• 11. Renal cortical necrosis

Very rare. Associated with acute renal failure... Case report: Nephrol Dial Transplant. 2001 Jan;16(1):189-90. Nephrol Dial Transplant1999; 14: 750?752

• 12. Retinal vascular obstruction

Very rare. A case of occlusion of the central retinal artery in a 75-year-old after taking the medicine... Case report: J Fr Ophtalmol. 1996;19(12):785-6.

• 13. Sickness

Infrequent.

• 14. Skin rash

Rare. Character bullous.. Case report: Ann Pharmacother. 1994 Nov;28(11):1305-6.

• 15. Stasis of the central retinal vein

Very rare. Presents with vision deficits; recovered after discontinuation of treatment... Case report: Retina. 1990;10(3):181-4.

• 16. Urinary clots

Rare. Patients with microscopic hematuria.. Case report: Br J Haematol. 1995 Mar;89(3):663-4.

• 17. Vascular thrombosis

Very rare. A fatal case of a patient with acute promyelocytic leukemia, in concurrence with the administration of trans retinoic acid... Case report: Leukemia. 1994 Jul;8(7):1113-5.

• 18. Vision loss

Very rare. A case report of blindness recoverable after IV administration of medication to a patient 52 with renal failure... Case report: Clin Exp Nephrol. 2003 Dec;7(4):311-4.

• 19. Vomit

Infrequent.