indapamide: What is, what is used for, dose, side effects, brands

INDAPAMIDE

Indications and usage
Important information
Before taking
How to use
While taking
Side effects
Brands

List of brands containing indapamide

This page contains a list of brands of authorized pharmaceutical specialties of the active principle indapamide in the countries listed below:

[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Indications and usage ▲

This drug is indicated for the treatment of hypertension of mild to moderate severity, alone or as part of a treatment with two or more therapeutic agents. Several government agencies have also authorized its use for the treatment of water and sodium retention associated with congestive heart failure.

Indapamide is a diuretic, the first of the indoline class, related pharmacologically with thiazide diuretics. Unlike others, this drug produces only a modest increase in urine volume.

Like other antihypertensive agents, indapamide does not cure hypertension but serves to control it, so treatment should be continued indefinitely unless directed by your doctor.

Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given indapamide.

Other ingredients of available commercial presentations:

Immediate-release tablets:

Besides the active ingredient, the tablets may include lactose, corn starch, magnesium stearate, polyvidone, talc, titanium dioxide, sodium lauryl sulfate, white beeswax, glycerol, macrogol 6000, methylcellulose, croscarmellose sodium, polyethylene glycol and coloring agents.

Extended-release tablets:

Besides 1.5 mg indapamide, the other ingredients include lactose monohydrate, povidone, hypromellose, colloidal anhydrous silica, magnesium stearate, opadry white (including polyvinyl alcohol, macrogol, titanium dioxide and talc).

Warning:

The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.

Important information ▲

The indapamide pharmaceutical specialties, both immediate-release tablets as extended-release tablets may contain lactose. If your doctor has told you that you suffer an intolerance to sugars, contact him before taking it.

Sports people: Indapamide may lead to a positive result in doping control tests

Before taking the drug ▲

Do not use indapamide

If you are allergic (hypersensitive) to indapamide, to some other sulfamide or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.

Allergy symptoms may include:

- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

Nor you should take this medicine:

- If you suffer from a serious kidney disease,
- If you have any severe liver disease or suffer from a condition called hepatic encephalopathy,
- If you have a low level of potassium in the blood,
- If you have recently suffered a stroke,
- If you are taking medication to treat heart arrhythmias since serious heartbeat alterations may occur,
- If you are pregnant or breastfeeding your baby.

Take special care with indapamide

- If you are dehydrated or are losing a lot of fluids (vomiting, diarrhea, or heavy sweating),
- If you have a liver disease,
- If you have diabetes mellitus,
- If you have hyperparathyroidism (an alteration of the parathyroid gland),
- If you suffer from lupus erythematosus,
- If you have gout, a joint disease due to elevated uric acid in the blood
- If you suffer from heart failure or other heart diseases, including coronary insufficiency,
- If you have any congenital cardiac arrhythmia or a family history of heart arrhythmia,
- If you have a kidney disease,
- If you are malnourished,
- If you will be subjected to a type of surgery called sympathectomy,
- If you are elderly,
- If you must undergo tests aimed at checking the functioning of the parathyroid gland
- If you have a history of photosensitivity (reaction in the skin by exposure to sunlight. This medicine may cause you become hypersensitive to sunlight and ultraviolet radiation. Therefore, you should minimize exposure to sunlight and UV rays.

Your doctor can check before starting treatment the level of potassium and calcium in the blood, doing this also repeatedly during the course of treatment.

Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.

If in doubt, consult your doctor.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.

It may be necessary to change the dose, or in some cases, discontinue one treatment. This applies to all types of drugs, but especially for:

Should not be taken indapamide simultaneously with Lithium (a medicine used to treat depression), since it raises the risk of lithium toxicity by increasing the level of the antidepressant.

If you are taking any of these medicines, must inform your doctor as he may need to take special precautions:

- Antiarrhythmic drugs and other therapeutic agents that can influence heart rate such as quinidine, hydroquinidine, disopyramide, amiodarone, sotalol, ibutilide, dofetilide, and digitális.
- Medicines to treat mental illnesses (antipsychotics, antidepressants, neuroleptics),
- Bepridil, a drug for the treatment of angina,
- Drugs capable of producing arrhythmia, as cisapride or diphemanil, a drug for the treatment of digestive disorders
- Quinolones, as moxifloxacin or sparfloxacin, antibacterial drugs,
- Halofantrine, a drug to treat certain types of malaria,
- Pentamidine, a medicine for the treatment of some pulmonary infections
- Mizolastine, an antiallergic drug,
- Nonsteroidal anti-inflammatory drugs (NSAIDs), commonly used to treat pain or inflammation drugs, such as ibuprofen or acetylsalicylic acid (aspirin)
- ACE inhibitors, for the treatment of hypertension and heart failure, as captopril, enalapril, etc.
- Corticosteroids, also known as cortisone derivatives, used to control inflammation and significant allergic reactions, such as asthma and chronic rheumatism,
- Stimulant laxatives peristalsis
- Baclofen, a muscle relaxant, used very often to combat muscle stiffness in diseases such as multiple sclerosis and other
- Potassium-sparing diuretics, as amiloride, spironolactone, and triamterene
- Metformin, a drug for the treatment of adult-onset diabetes,
- Iodinated contrasts, substances used to carry out radiological tests,
- Calcium supplements, either in the form of tablets or incorporated in some enriched foods with this substance,
- immunosuppressant drugs, used to prevent rejection of transplants, as cyclosporin, Tacrolimus, and other agents
- Tetracosactide, a drug for the treatment of ulcerative colitis, Crohn's disease, multiple sclerosis and other

Use with food and beverages

This medicine may be taken with meals or out of them. Alcohol intake should be avoided because it may potentiate some adverse effects of indapamide.

Special physiological situations

Pregnancy and lactation:

Always consult your doctor or pharmacist before taking any medicine during pregnancy or breastfeeding.

As a general rule, diuretics should not be given to pregnant women nor should be used to treat the physiological edema(swelling) of the pregnancy. Diuretics can cause an increased risk of fetal growth retardation.

Studies in laboratory animals at doses several times higher than the usual for human revealed no fetal malformations or impairment of fertility.

However, the effect of the drug on animals is not predictive of its effect on people, and for this reason, its use is advisable only when is clearly necessary and can not be replaced by an alternative drug better known and safe enough.

Some disorders may occur with the use of this medicine, such as fetal or neonatal jaundice (yellowing of the skin and/or conjunctive), thrombocytopenia (low platelets) and other side effects.

Lactation

Indapamide is excreted through breast milk, so it is not recommended to breastfeed the baby while the medicine is used. If the indapamide use in lactating women is considered essential, breastfeeding should be discontinued.

Children:

Have not been established the efficacy and safety of this drug in children, so it should not be used in this age group.

Elderly:

Available studies have not included a sufficient number of patients aged 65 or more years for determining if their behavior is different than younger patients, although available data do not show differences with regard to other adults younger. In general, is recommended to start treatment in older people with the lowest possible doses (1.25 mg, for example).

Driving and using machines

Indapamide does not affect the alertness or directly to driving itself, but can produce certain reactions in specific cases (dizziness, fatigue or weakness) due to the reduction in blood pressure, especially at the beginning of treatment or when added another antihypertensive agent. For this reason, it may be affected the ability to drive or operate potentially dangerous machinery. Before doing these tasks, it is advisable to check how can affect you this drug.

How to use indapamide ▲

Follow carefully instructions of use of indapamide provided by your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given on this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.

The usual dose is one tablet a day, preferably in the morning. The initial dose will be prescribed by your doctor among those available (1.25, 1.5 and 2.5 mg respectively). This can be modified by your doctor, without exceeding 2.5 mg daily. The tablets should be swallowed whole, helping with a glass of water. Do not break or chew the tablets.

Note that indapamide does not cure hypertension, but serves to keep it under control. For this reason, the treatment must be maintained without interruption, unless your doctor changes the treatment of the disease.

If you think the effect of the medicine is too strong or too weak, consult your doctor.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

While you take indapamide ▲

If a doctor prescribes another medicine, tell you are taking indapamide.

Check with your doctor regularly developments of disorder that motivates the use of indapamide. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.

Do not restart treatment with indapamide at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.

If you feel unwell during treatment with indapamide, immediately consult your doctor.

If you take more than you should:

Consult your doctor or pharmacist. A very high dose of indapamide may cause nausea, vomiting, an excessive drop in blood pressure, dizziness, cramps, drowsiness, confusion and increased urination.

If you think you have taken too much medicine, tell your doctor immediately or go to the emergency room of the nearest hospital. Take the pack and the rest of unconsumed medicine, even though you feel well.

If you forget to take indapamide

Wait until be the time for the next dose. Do not take a double dose to make up for forgotten individual doses.

If you stop taking indapamide

You should not stop treatment unless your doctor tells you since blood pressure may rise again.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Side Effects of indapamide ▲

Like all medicines, indapamide can cause side effects although not everybody gets them.

The frequency of side effects is classified into:

Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data

Common side effects

- Decreased level of potassium, which can cause muscle weakness.
- Allergic reactions, mainly dermatological, such as rashes, especially in people predisposed to such reactions.

Uncommon side effects:

- Vomiting
- Purpuric rash or simply purple, consisting of the appearance of dots or red spots on the skin.

Rare side effects

- Tiredness dizziness headache paresthesia (sensation of tingling)
- Digestive symptoms, such as nausea constipation or dry mouth, < br /> - Increased risk of dehydration, particularly in the elderly and in patients with congestive heart failure.

Very rare side effects:

- Hypotension
- Heart rhythm disturbances
- kidney disorders
- Inflammation of the pancreas (pancreatitis)
- Liver disorders,
- Blood disorders, as anemia (decreased red blood cells), thrombocytopenia (decreased number of platelets), which can manifest by bruising, bruising or nosebleeds leucopenia (low white blood cells), which can lead to severe complications by decreasing organic defenses
- skin allergic reactions, as angioedema and urticaria. Angioedema manifests as a sudden swelling of a body part, especially on the face, which can be very serious if it causes obstruction of the respiratory or digestive tract. This is a medical emergency that must be addressed immediately.

As with thiazide diuretics have been reported sensitivity reactions to sunlight and ultraviolet radiation. Patients treated with indapamide should be exposed to direct sunlight with extreme caution, taking into account this possibility.

Side effects of unknown frequency:

- Disturbances electrocardiogram and heart rhythm disturbances that can endanger the patient's life (torsades de pointes)
- Hepatitis. If severe functional liver failure occurs, the patient may also suffer a brain disorder known as hepatic encephalopathy
- Worsening symptoms of lupus erythematosus
- Syncope or fainting

Alteration of laboratory tests

- Decreased blood potassium
- Decreased blood sodium
- Elevation of uric acid in the blood
- Elevation of blood glucose in patients with previous diabetes
- calcium elevation in blood
- Elevation of liver enzymes (transaminases, alkaline phosphatase).

This list does not include all adverse reactions associated with the use of indapamide, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.

If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.

If any of the side effects gets serious, tell your doctor or pharmacist.

List of brands containing indapamide ▲

This page contains list of brands of authorized pharmaceutical specialties of the active principle indapamide in the countries listed below:

[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Warning:

With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.

Australia: ▲

APO-INDAPAMIDE SR 1.5 mg, 90 extended-release tablets
CHEMMART INDAPAMIDE 2.5 mg, 90 tablets
CHEMMART INDAPAMIDE SR 1.5 mg, 90 extended-release tablets
DAPA-TABS 2.5 mg, 90 tablets
GENRX INDAPAMIDE 2.5 mg, 90 tablets
INDAPAMIDE-GA 2.5 mg, 90 tablets
INDAPAMIDE AN SR 1.5 mg, 90 extended-release tablets
INSIG 2.5 mg, tablets
INDAPAMIDE AN 2.5 mg, 60-90 tablets
INDAPAMIDE SANDOZ 2.5 mg, 90 tablets
NAPAMIDE 2.5 mg, 90 tablets
NATRILIX 2.5 mg, 90 tablets
NATRILIX SR 1.5 mg, 30-90 extended-release tablets
ODAPLIX SR 1.5 mg, 90 tablets
TERRY WHITE CHEMISTS INDAPAMIDE 2.5 mg, 90 tablets
TERRY WHITE CHEMISTS INDAPAMIDE SR 1.5 mg, 90 extended-release tablets
TENAXIL SR 1.5 mg, 90 extended-release tablets

Brazil: ▲

INDAPEN SR 1.5 mg, 30 extended-release tablets
NATRILIX 2.5 mg, 15 y 30 dragees
NATRILIX SR 1.5 mg, 15- 30 extended-release tablets

Canada: ▲

APO-INDAPAMIDE 1.25 mg, 30-100 tablets
APO-INDAPAMIDE 2.5 mg, 30-100 tablets
DOM-INDAPAMIDE 1.25 mg, 30-100 tablets
DOM-INDAPAMIDE 2.5 mg, 30-100 tablets
JAMP-INDAPAMIDE 1.25 mg, 30-100 tablets
JAMP-INDAPAMIDE 2.5 mg, 30-100 tablets
LOZIDE 1.25 mg, 30-100 tablets
LOZIDE 2.5 mg, 30-100 tablets
MYLAN-INDAPAMIDE 1.25 mg, 30-100 tablets
MYLAN-INDAPAMIDE 2.5 mg, 30-100 tablets
NOVO-INDAPAMIDE 2.5 mg, 30-100 tablets
PHL-INDAPAMIDE 1.25 mg, 30-100 tablets
PHL-INDAPAMIDE 2.5 mg, 30-100 tablets
PMS-INDAPAMIDE 1.25 mg, 30-100 tablets
PMS-INDAPAMIDE 2.5 mg, 30-100 tablets
PRO-INDAPAMIDE 1.25 mg, 30-100 tablets
PRO-INDAPAMIDE 2.5 mg, 30-100 tablets
RIVA-INDAPAMIDE 1.25 mg, 30-100 tablets
RIVA-INDAPAMIDE 2.5 mg, 30-100 tablets

France: ▲

FLUDEX 1.5 mg, extended-release tablets
FLUDEX 2.5 mg, tablets
INDAPAMIDE ARROW 1.5 mg, extended-release tablets
INDAPAMIDE BIOGARAN 1.5 mg, extended-release tablets
INDAPAMIDE BIOGARAN 2.5 mg, tablets
INDAPAMIDE EG LP 1.5 mg, extended-release tablets
INDAPAMIDE ISOMED LP 1.5 mg, extended-release tablets
INDAPAMIDE KRKA LP 1.5 mg, extended-release tablets
INDAPAMIDE MYLAN 2.5 mg, tablets
INDAPAMIDE MYLAN LP 1.5 mg, extended-release tablets
INDAPAMIDE QUALIMED L.P 1.5 mg, extended-release tablets
INDAPAMIDE RANBAXY LP 1.5 mg, extended-release tablets
INDAPAMIDE RATIOPHARM LP 1.5 mg, extended-release tablets
INDAPAMIDE SANDOZ LP 1.5 mg, extended-release tablets
INDAPAMIDE TEVA LP 1.5 mg, extended-release tablets
INDAPAMIDE TEVA SANTE LP 1.5 mg, extended-release tablets
INDAPAMIDE ZENTIVA LP 1.5 mg, extended-release tablets
INDAPAMIDE ZYDUS LP 1.5 mg, extended-release tablets

Germany: ▲

INDAPAMID-ACTAVIS 1.5 mg, extended-release tablets
INDAPAMID-ACTAVIS 2.5 mg, capsules
INDAPAMID AL 1.5 mg, extended-release tablets
INDAPAMID BIOEQ PHARMA 1.5 mg, extended-release tablets
INDAPAMID-CT 2.5 mg, capsules
INDAPAMID HEUMANN 1.5 mg, extended-release tablets
INDAPAMID HEUMANN 2.5 mg, tablets
INDAPAMID-RATIOPHARM 1.5 mg, extended-release tablets
INDAPAMID STADA 1.5 mg, extended-release tablets
NATRILIX 2.5 mg, tablets
NATRILIX SR 1.5 mg, extended-release tablets

India: ▲

CGNIDE SR1.5 mg, extended-release tablets
DIURIX1.5 mg, extended-release tablets
DIURIX 2.5 mg, tablets
DIURIX1.5 mg, extended-release tablets
DIVRET1.5 mg, extended-release tablets
FANTON 2.5 mg, tablets
IN-SR1.5 mg, extended-release tablets
IND-SR1.5 mg, extended-release tablets
INDOCARD1.5 mg, extended-release tablets
INDACT 2.5 mg, tablets
INDACT-SR1.5 mg, extended-release tablets
INDAP 2.5 mg, tablets
INDAP1.5 mg, extended-release tablets
INDICONTIN CR 1.5 mg, controlled release capsules
INZU 1.5 mg, extended-release tablets
LORVAS1.5 mg, extended-release tablets
LORVAS 2.5 mg, tablets
NATRILIX1.5 mg, extended-release tablets
NATRILIX 2.5 mg, tablets
PERIFER 2.5 mg, tablets

Italy: ▲

DAMIDE 2.5 mg, capsules
INDAFLEX 2.5 mg, capsules
INDAMOL 2.5 mg, tablets
INDAPAMIDE MYLAN 2.5 mg, tablets
INDAPAMIDE MYLAN1.5 mg, extended-release tablets
INDAPAMIDE PENSA 2.5 mg, tablets
INDAPAMIDE PLIVA 2.5 mg, tablets
INDAPAMIDE SANDOZ 2.5 mg, tablets
IPAMIX 2.5 mg, tablets
MILLIBAR 2.5 mg, capsules
NATRILIX 2.5 mg, tablets
NATRILIX LP1.5 mg, extended-release tablets
PRESSURAL 2.5 mg, tablets
VEROXIL 2.5 mg, tablets

Japan: ▲

NATRIX 1 mg, tablets
NATRIX 2 mg, tablets
TENAXIL 1 mg, tablets
TENAXIL 2 mg, tablets

Mexico: ▲

NATRILIX SR 1.5 mg, 30 extended-release tablets

Pakistan: ▲

BAPLOW 2.5 mg, tablets
HYPOMIDE 2.5 mg, tablets
HYPOMIDE1.5 mg, extended-release tablets
INDURIN 2.5 mg, tablets
NATRILIX 2.5 mg, tablets
NATRILIX1.5 mg, extended-release tablets

Spain: ▲

EXTUR 2.5 mg, 30 tablets
INDAPAMIDA APOTEX 1.5 mg 30 extended-release tablets
INDAPAMIDA MYLAN 2.5 mg, 30 tablets
INDAPAMIDA NORMON 2.5 mg, 30 tablets
INDAPAMIDA RETARD CINFA 1.5 mg 30 extended-release tablets
INDAPAMIDA RETARD KERN PHARMA 1.5 mg 30 extended-release tablets
INDAPAMIDA RETARD MABO 1.5 mg 30 extended-release tablets
INDAPAMIDA RETARD MYLAN 1.5 mg 30 extended-release tablets
INDAPAMIDA RETARD PENSA 1.5 mg 30 extended-release tablets
INDAPAMIDA RETARD SANDOZ 1.5 mg 30 extended-release tablets
INDAPAMIDA RETARD TEVA 1.5 mg 30 extended-release tablets
TERTENSIF 2.5 mg, 30 tablets
TERTENSIF RETARD 1.5 mg 30 extended-release tablets

Turkey: ▲

FLUBEST SR 1.5 mg 30 extended-release tablets
FLUDEX SR 1.5 mg 30-ended-release tablets
FLUDIN 2.5 mg, 30 tablets
FLUPAMID 2.5 mg, 30 tablets
FLUPAMID SR 1.5 mg 30-90 extended-release tablets
FLUTANS 2.5 mg, 30 tablets
INDADAY SR 1.5 mg 30 extended-release tablets
INDAPEN 2.5 mg, 30 tablets
INDURIN 2.5 mg, 30 tablets
INDURIN SR 1.5 mg 30 extended-release tablets

United Kingdom: ▲

ALKAPAMID XL 1.5 mg, prolonged-release tablets
INDAPAMIDE AAH PHARMA 2.5 mgs 28-30-56 tablets
INDAPAMIDE AAH PHARMA 1.5 mg, 30 modified-release tablets
INDAPAMIDE ALLIIANCE HEALTHCARE 2.5 mg, 56 tablets
INDAPAMIDE CO- PHARMA 2.5 mg, 28 tablets
INDAPAMIDE KENT PHARMA 2.5 mg, 28-56 tablets
INDAPAMIDE KENT PHARMA 1.5 mg, 30 modified-release tablets
INDAPAMIDE GENERICS 2.5 mg, 28-56 tablets
INDAPAMIDE NICHE GENERICS 2.5 mg, 28 tablets
INDAPAMIDE ZENTIVA 2.5 mg, 28-56 tablets
INDIPAM XL 1.5 mg, 28-30 modified-release tablets
NATRILIX 2.5 mg, tablets
NATRILIX SR 1.5 mg, 30 modified-release tablets
RAWEL XL 1.5 mg, 30 modified-release tablets
TENSAID XL 1.5 mg, 30 modified-release tablets
VARBIM XL 1.5 mg, 30 modified-release tablets

U.S.A. and Puerto Rico: ▲

INDAPAMIDE ALPHAPHARM 1.25 mg, 100 tablets
INDAPAMIDE ALPHAPHARM 2.5 mg, 100 tablets
INDAPAMIDE REMEDYREPACK 2.5 mg, blister 30 tablets
INDAPAMIDE ACTAVIS ELIZABETH 1.25 mg, 100 tablets
INDAPAMIDE ACTAVIS ELIZABETH 2.5 mg, 100 tablets
INDAPAMIDE LAKE ERIE 1.25 mg, 100 tablets
INDAPAMIDE MYLAN 1.25 mg, 100 tablets
INDAPAMIDE MYLAN 2.5 mg, 90-100 tablets
INDAPAMIDE PHYSICIAN TOTAL CARE 1.25 mg, 30-100 tablets
INDAPAMIDE PHYSICIAN TOTAL CARE 2.5 mg, 30- 60-90-100 tablets
INDAPAMIDE REBEL 1.25 mg, 30 tablets
INDAPAMIDE UDL 2.5 mg, 100 tablets
LOZOL 1.25 mg, 100 tablets

Page updated: December 11, 2010.