Do not use norfloxacin
If you are allergic (hypersensitive) to norfloxacin or any of other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.
Allergy symptoms may include:
- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).
Nor you should take this medicine:
If you have or have had a tendonitis or tendon rupture as result of administration of norfloxacin or other fluoroquinolone.
Take special care with norfloxacin
Tell your doctor about any illness you have or have had, especially:
- Allergy to any antibiotic
- A liver problem
- You have or have had tendon problems
- You suffer a disease that causes muscle weakness, such as myasthenia gravis
- You have a disease of central nervous system such as epilepsy or a history of seizures
- You suffer from nerves
- You or a relative suffer from some form of arrhythmia, such as QTc prolongation or bradycardia (slow heartbeat)
- You have low potassium in the blood
- Your kidney works abnormally, since you require a lower dose of the drug
- You have rheumatoid arthritis or a history of joint problems
- You are pregnant or planning to become pregnant
In case of using solution for ophthalmic use (eye drops):
- Tell your doctor if you suffer eye irritation or redness or eyelid swelling
- Stop treatment and seek medical attention if you think the medicine may be causing an allergic reaction such as rash or redness and itching of the eye
- Tell your doctor if you think you may be worsening your eye infection or if you have a new eye injury or new symptoms
- Tell your doctor if you will undergo an ocular surgery or if you suffer a reaction, including new symptoms or worsening of previous symptoms..
Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.
If in doubt, consult your doctor.
Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.
You should tell your doctor especially if you are being treated with:
- Nonsteroidal antiinflamatory drugs (NSAIDs) . Some of available substances to treat pain and inflammation may increase risk of nervous system effects, especially seizures
- Glibenclamide (glyburide)
- Oral anticoagulants (acenocoumarol, warfarin)
- Antiarrhythmic, such as quinidine, amiodarone or procainamide
- Antipsychotics, specially clozapine
- Tricyclic antidepressants
- Erythromycin
- Sotalol
- Diuretics
- Corticosteroids
- Probenecid
- Cyclosporine
- Caffeine or products containing it (norfloxacin may increase the effects of this substance)
- Ropinirole
- Tacrine
- Tizanidine
- Theophylline
- Cisapride (a medicine not authorized in many countries).
Some medicines can prevent proper absorption of norfloxacin:
- Sucralfate
- Antacids
- Some multivitamin formulations and other specialties containing iron or zinc
- Didanosine
These pharmaceuticals must be taken two hours before norfloxacin for not to interfere with its absorption.
You should not take nitrofurantoin while receiving norfloxacin.
Use with food and beverages
This medicine should be taken with a glass of water, at least one hour before or two hours after eating or drinking milk.
Consult your doctor or pharmacist before taking any medicine.
Special physiological situations
Pregnancy and lactation
Always consult your doctor or pharmacist before taking any medicine during pregnancy or lactation.
It is not known whether norfloxacin can cause harm to your unborn child. If you are pregnant, you plan to become pregnant or may become pregnant, tell your doctor, who will assess the possible benefits of using this medicine against the potential risks of its administration.
This medication passes through breast milk to nursing infant. Consult your doctor and follow his guidance on whether or not to continue the treatment and/or discontinue breastfeeding.
Use in children
The administration of norfloxacin is not recommended in children and adolescents below 18 years.
Driving and using machines
Some patients experience dizziness while taking the drug, so it is advisable to know how you react during treatment before driving or operating dangerous machinery. The eye drops can also affect the ability for driving, so you should try first to administer it before driving or using machinery.
Consult your doctor or pharmacist before taking any medicine.
Like all medicines, norfloxacin can cause side effects, although not everybody gets them.
The frequency of side effects is classified into:
Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data
In general, this medication is usually well tolerated. The most common adverse reactions are:
- Nausea,
- Headache,
- Dizziness,
- Rash,
- Heartburn,
- Abdominal pain or cramping,
- Diarrhea,
- Weakness,
- Abnormal liver tests.
Norfloxacin can lead to side effects that can be severe or even very severe.
Important side effects:
Central nervous system side effects:
There have been reports of seizures in patients taking fluoroquinolones, including norfloxacin. Tell your doctor if you have a history of seizures. Ask your doctor tells you how you can change your risk of new episodes of seizures.
Neurological effects may manifest even after the first dose, and include:
- Feel dizzy
- seizures
- Hearing voices, seeing or feeling things that are not there (hallucinations)
- Feeling restless
- Tremor
- Anxiety or nervousness
- Confusion
- Have suspicions of other people or situations (paranoid ideas)
- Peripheral neuritis. It is a nerve disorder usually located on a limb (foot, hand, arm, leg, etc.). Discontinue treatment and consult your doctor if you notice pain, burning, numbness, tingling and/or weakness. You must stop treatment with fluoroquinolone to prevent the nerve suffers permanent damage.
Allergic reactions:
They are very rare. Allergic reactions can be important even after a single dose. If you are in this case or you think so, go immediately to the emergency department of the nearest hospital.
These allergic reactions include urticaria (hives), difficulty breathing or swallowing, swelling of lips, fast or very fast heartbeat , tightness in the throat, hoarseness, rash, with or without fever and feeling unwell and weakness, yellowing of the whites of the eyes or skin (jaundice). In any of these cases, consult your doctor.
Abnormal heart rhythm:
Although rarely, may occur a significant heart rhythm disturbances such as QTc prolongation and torsades de pointes. Tell your doctor if you notice changes in your heart rate (faster or slower, irregular heartbeat, etc.) or feel weak. These alterations are more frequent in patients with a family history of QTc prolongation, low blood potassium or who are taking anti-arrhythmic.
Skin disorders:
It can occur a rash, even after taking a single dose. Stop treatment immediately at the first sign of rash (spots or hives), as it may be indicative of a most important adverse reaction
Intestinal infections:
Pseudomembranous colitis is a complication of antibiotic therapy, that many drugs can provoke, not only norfloxacin. Contact your doctor if you experience watery and/or bloody diarrhea. This disease can be accompanied by fever and abdominal cramps. The disorder may even appear several weeks after completing antibiotic treatment.
Hypoglycemia (low blood sugar):
The combination of a fluoroquinolone and glibenclamide may lead to a drop in blood glucose which sometimes may be large. Tell your doctor you are being treated with this oral anti-diabetic and if you experience downs of glucose level while taking norfloxacin, since may be advisable to change the antibiotic.
Photosensitivity:
As indicated above, you should take precautions to avoid prolonged sun exposure while taking norfloxacin.
Rupture or swelling of tendons:
This is a serious side effect that can occur with a quinolone in patients of all ages. These lesions are located preferably in large tendons, such as Achilles tendon, shoulders, hands and elsewhere. The risk of suffering this complication is higher in patients over 60 years, people undergoing treatment with corticosteroids or have had a transplant of kidney, heart or lung, although are also more likely to suffer that condition those with previous osteoarticular problems, including chronic inflammatory diseases such as rheumatoid arthritis, kidney failure or which perform regularly physical activity.
Tendon rupture can occur while taking the drug or afterwards.
If you suspect you have an inflammation or tendon rupture, immediately consult your doctor. The break may present signs and symptoms such as crunching or clicking of tendon, bruising after the traumatism, inability to move the injured limb or bear weight upon extremity
Aggravation of a preexisting myasthenia gravis:
Fluoroquinolones can worsen clinical manifestations of myasthenia gravis, especially muscle weakness and difficulty breathing. If you have this muscular disorder consult your doctor before taking any fluoroquinolone including norfloxacin.
Other side effects:
- Vaginal infections by candida albicans with itching or burning (uncommon)
- Low white blood cells (uncommon)
- Anemia (very rare)
- Disorder blood clotting (rare)
- Loss of appetite (uncommon)
- Depression, sleep disturbances (uncommon)
- Disorientation, nervousness, irritability, anxiety, hallucinations, psychic disturbances, confusion, tremor (rare)
- Psychotic reactions (very rare)
- Alteration or loss of taste (ageusia, dysgeusia) (uncommon)
- Weakness, burning and tingling, fever, contraction and muscle weakness (very rare)
- Tearing, visual disturbances (rare)
- Tinnitus (rare)
- Hearing Loss (very rare)
- Inflammation of blood vessels (very rare)
- Difficulty breathing (rare)
- Inflammation of colon and pancreas (very rare)
- Jaundice (rare)
- Hepatitis (very rare)
- Muscle or joint pain (rare)
- Hematuria (blood in urine), renal failure (very rare)
- Increased muscle enzymes in blood (very rare)
Other adverse reactions with possible relationship cause-effect (although this relationship is not well established):
- Conjunctivitis, ocular discomfort (pain, irritation, redness)
- Fatigability, drowsiness, constipation and flatulence
- Muscular hypertonicity, muscular incoordination, slurred speech, fever, vomiting.
This list not includes all adverse reactions associated with the use of norfloxacin, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.
If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.
If any of the side effects gets serious, tell your doctor or pharmacist.
This page contains list of brands of authorized pharmaceutical specialties of the active principle norfloxacin in the countries listed below:
[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]
Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.
Warning:
With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.
Australia: ▲
APO-NORFLOXACIN 400 mg, tablets
CHEMMART NORFLOXACIN 400 mg, tablets
GENRX NORFLOXACIN 400 mg, tablets
GN-NORFLOXACIN 400 mg, tablets
LAXIFLOCIN 400 mg, tablets
NORFLOXACIN AN 400 mg, tablets
NORFLOXACIN-AS 400 mg, tablets
NORFLOXACIN ASCENT 400 mg, tablets
NORFLOXACIN-GA 400 mg, tablets
NORFLOXACIN SANDOZ 400 mg, tablets
NORFLOXACIN WATSON 400 mg, tablets
NUFLOXIB 400 mg, tablets
ROXIN 400 mg, tablets
TERRY WHITE CHEMISTS NORFLOXACIN 400 mg, tablets
Brazil: ▲
ANDROFLOXIN 400 mg, 14 tablets
FLOX 400 mg, 14 tablets
FLOXACIN 400 mg, 6 & 14 tablets
FLOXATRAT 400 mg, 14 tablets
FLOXIMED 400 mg, 14 tablets
FLOXINOL 400 mg, 6 & 14 tablets
NEOFLOXIN 400 mg, 14 tablets
NORF 400 mg, 14 tablets
NORFLOXACINO BIOSINTETICA 400 mg, 7 & 14 tablets
NORFLOXACINO BRAINFARMA 400 mg, 6 & 14 tablets
NORFLOXACINO EMS 400 mg, 14 tablets
NORFLOXACINO GERMED 400 mg, 14 tablets
NORFLOXACINO GLOBO 400 mg, 14 tablets
NORFLOXACINO LEGRAND 400 mg, 14 tablets
NORFLOXACINO MEDLEY 400 mg, 6 & 14 tablets
NORFLOXACINO MEPHA-RATIOPHARM 400 mg, 6 & 14 tablets
NORFLOXACINO MERCK 400 mg, 6 & 14 tablets
NORFLOXACINO MULTILAB 400 mg, 14 tablets
NORFLOXACINO NEO QUIMICA 400 mg, 6 & 14 tablets
NORFLOXACINO PRATI DONADUZZI 400 mg, 7 & 14 tablets
NORFLOXACINO RANBAXY 400 mg, 6 & 14 tablets
NORFLOXACINO SANDOZ 400 mg, 14 tablets
NORFLOXACINO TEUTO 400 mg, 14 tablets
NORFLOXACINO UNIAO QUIMICA 400 mg, 6 & 14 tablets
NORFLOXAN 400 mg, 14 tablets
NORFLOXMED 400 mg, 14 tablets
NORFLURIN 400 mg, 14 tablets
NORXACIN 400 mg, 14 tablets
QUINOFORM 400 mg, 14 tablets
RESPEXIL 400 mg, 6 & 14 tablets
UNI NORFLOXACIN 400 mg, 14 tablets
URITRAT 400 mg, 6 & 14 tablets
UROSEPTAL 400 mg, 6 & 20 tablets
UROXAZOL-N 400 mg, 14 tablets
Canada: ▲
APO-NORFLOX 400 mg, tablets
AVA-NORFLOXACIN 400 mg, 100 tablets
CO NORFLOXACIN 400 mg, 100 tablets
NOVO-NORFLOXACIN 400 mg, 100 tablets
PMS-NORFLOXACIN 400 mg, 100 tablets
RIVA-NORFLOXACIN 400 mg, 100tabletas
France: ▲
CHIBROXINE 0.3%, eye drops
NORFLOXACINE ARROW 400 mg,tablets
NORFLOXACINE BIOGARAN 400 mg,tablets
NORFLOXACINE CRISTERS 400 mg,tablets
NORFLOXACINE EG 400 mg,tablets
NORFLOXACINE MYLAN 400 mg,tablets
NORFLOXACINE QUALIMED 400 mg,tablets
NORFLOXACINE RANBAXY 400 mg,tablets
NORFLOXACINE RATIOPHARM 400 mg,tablets
NORFLOXACINE SANDOZ 400 mg,tablets
NORFLOXACINE TEVA 400 mg,tablets
NORFLOXACINE ZENTIVA 400 mg,tablets
NOROXINE 400 mg,tablets
Germany: ▲
BARAZAN 400 mg,tablets
NORFLOHEXAL 400 mg,tablets
NORFLOSAL 400 mg,tablets
NORFLOX-1 A PHARMA 400 mg,tablets
NORFLOX-CT 400 mg,tablets
NORFLOX-SANDOZ 400 mg,tablets
NORFLOXACIN ABZ 400 mg,tablets
NORFLOXACIN AL 400 mg,tablets
NORFLOXACIN HEYUMANN 400 mg,tablets
NORFLOXACIN-RATIOPHARM 400 mg,tablets
NORFLOXACIN STADA 400 mg,tablets
NORFLUXX 400 mg,tablets
India: ▲
ACTIFLOX-400 400 mg, tablets
ALFLOX 400 mg, tablets
ALFLOX 100 mg, dispersible tablets
ANQUIN 400 mg, tablets
BACIGYL 400 mg, tablets
BACIGYL 20 mg/ml, oral suspension
BIOFLOXIN 400 mg, tablets
DENAR 100 mg, dispersible tablets
ENTEROFLOX 400 mg, tablets
FLOX 400 mg, tablets
FLOX 20 mg/ml, oral suspension
HARFLOX 0.3%, eye drops
LOXONE 400 mg, tablets
MERIFLOX 400 mg, tablets
N-FLOX 0.3%, eye drops
NEGAFLOX 400 mg, tablets
NITDIN 100 mg, dispersible tablets
NITDIN 400 mg, tablets
NOR-U 400 mg, tablets
NORALAX 400 mg, tablets
NORBACTIN 200 mg, tablets
NORBACTIN 400 mg, tablets
NORBACTIN 0.3%, eye drops
NORBID 100 mg, dispersible tablets
NORBID 200 mg, tablets
NORBID 400 mg, tablets
NORFLOX 100 mg, dispersible tablets
NORFLOX 200 mg, tablets
NORFLOX 400 mg, tablets
NORFLOX 800 mg, tablets
NORFLOX 0.3%, eye/ear drops
NORFLOX 0.3%, eye ointment
NORILET 200 mg, tablets
NORILET 400 mg, tablets
NORILET 0.3%, eye/ear drops
NORILET-D 0.3%, eye/ear drops
NORIN 400 mg, tablets
NORMAX 400 mg, tablets
NORVIT 0.3%, eye drops
NOX 400 mg, tablets
OPTOFLOX 0.3%, eye drops
PD-NOR 0.3%, eye/ear drops
POWERFLOX 100 mg, dispersible tablets
PROGEN 0.3%,ear drops
QUINOBID 200 mg, tablets
QUINOBID 400 mg, tablets
QUINOLOX 400 mg, tablets
RENOR 0.3%, eye drops
SIANOR 0.3%, eye drops
SIANOR 400 mg, tablets
TAMFLOX 400 mg, tablets
UFLOX 400 mg, tablets
UFLOX 400 mg, tablets
URIBEN 400 mg, tablets
UROFLOX 400 mg, tablets
UTIBID 400 mg, tablets
ZEFLOX 100 mg, dispersible tablets
ZEFLOX 400 mg, tablets
Italy: ▲
DIPERFLOX 5.4%, oral suspension
DIPERFLOX 540 mg, tablets
FLOSSAC 400 mg, capsules
NAFLOX 0.3%, eye drops
NAFLOX 0.3%, single-dose eye drops
NORFLOX 5.4%, oral suspension
NORFLOX 540 mg, tablets
NORFLOXACINA ABC 400 mg, capsules
NORFLOXACINA ACTAVIS 400 mg, tablets
NORFLOXACINA AUROBINDO 400 mg, tablets
NORFLOXACINA DR. REDDY'S 400 mg, capsules
NORFLOXACINA EG 400 mg, tablets
NORFLOXACINA SANDOZ 400 mg, tablets
NOROXIN 400 mg, tablets
RENOXACIN 400 mg, tablets
SEBERCIM 400 mg, tablets
THEANORF 0.3%, eye drops
UTICINA 400 mg, tablets
UTINOR 400 mg, tablets
Japan: ▲
BACCIDAL CHILDREN 50 mg, tablets
BACCIDAL 100 mg, tablets
BACCIDAL 200 mg, tablets
BASTEEN 100 mg, tablets
BASTEEN 200 mg, tablets
NORFLOXACIN EMEC 100 mg, tablets
NORFLOXACIN EMEC 200 mg, tablets
NORFLOXACIN TSURUHARA 100 mg, tablets
NORFLOXACIN TSURUHARA 200 mg, tablets
NORFLOXACIN YD 100 mg, tablets
NORFLOXACIN YD 200 mg, tablets
XAFLOR 100 mg, tablets
XAFLOR 200 mg, tablets
Mexico: ▲
AXOFLANOL 400 mg, tablets
BACCIDAL 400 mg, 14 tablets
BAXAMED 400 mg, 20 tablets
DIFOXACIL 400 mg, 14 tablets
EXYN-T 3 mg/ml, 5 ml eye drops
FLOXACIN 400 mg, 14 & 20 tablets
MICROXIN 400 mg, 14 & 20 tablets
MINIBIOT N 400 mg, 20 tablets
NOFLOROX 400 mg, 10 & 20 tablets
NOROXIN 400 mg, 20 tablets
NORQUINOL 400 mg, 20 dragees
ORANOR 400 mg, 10 & 20 tablets
Pakistan: ▲
ALBACT 200 mg, tablets
AL FLOX 400 mg, tablets
ALENBIT 400 mg, tablets
AXONOR 400 mg, tablets
BACCIDAL 400 mg, tablets
BACTINOR 400 mg, tablets
BACTINOR 3 mg/ml, eye drops
ECOFLAXIN 400 mg, tablets
FLONOX 3 mg/ml, eye drops
FLOXANOR 400 mg, tablets
FLOXIN 400 mg, tablets
FYNKLOCIN 400 mg, tablets
GLOSIFLOX 400 mg, tablets
HELINOX 400 mg, tablets
JNOR 400 mg, tablets
LONAR 400 mg, tablets
MEDI-NOR 400 mg, tablets
NEFROLON 400 mg, tablets
NEFROX 400 mg, tablets
NEWSEDAL 400 mg, tablets
NF-400 400 mg, tablets
NOACIN 400 mg, tablets
NOCIN 400 mg, tablets
NOLICIN 400 mg, tablets
NORASIA 400 mg, tablets
NORFLOMED 400 mg, tablets
NORFLOSAF 400 mg, tablets
NORISH 400 mg, tablets
NOROCIN 400 mg, tablets
NOROQUINE 400 mg, tablets
NOROXIN 400 mg, tablets
NOROXO 400 mg, tablets
NORTEC 400 mg, tablets
NORYAN 400 mg, tablets
NOXACIN 400 mg, tablets
OLONAF 400 mg, tablets
QUNOR 400 mg, tablets
RENOR 400 mg, tablets
ROBINEX 400 mg, tablets
SILNOR 400 mg, tablets
TRIZOLIN 400 mg, tablets
UNIQUE 400 mg, tablets
URA 400 mg, tablets
URAC 400 mg, tablets
URACIN 400 mg, tablets
URID 400 mg, tablets
URIFLOX 400 mg, tablets
URITAC 400 mg, tablets
UROQUIN 400 mg, tablets
UTIBEX 400 mg, tablets
WEBNOR 400 mg, tablets
ZOROXIN 400 mg, tablets
Spain: ▲
CHIBROXIN 3 mg/ml, 5 ml eye drops
ESCLEBIN 400 mg, 14 tablets
NORFLOXACINO BEXAL 400 mg, 14 tablets
NORFLOXACINO CINFA 400 mg, 14 tablets
NORFLOXACINO NORMON 400 mg, 14 tablets
NORFLOXACINO PENSA 400 mg, 14 tablets
NORFLOXACINO QUALIGEN 400 mg, 14 tablets
NORFLOXACINO RANBAXY 400 mg, 14 tablets
NORFLOXACINO SANDOZ 400 mg, 14 tablets
NORFLOXACINO STADA 400 mg, 14 tablets
NOROXIN 400 mg, 14 tablets
XASMUN 400 mg, 14 tablets
Turkey: ▲
NOROXIN 400 mg, tablets
United Kingdom: ▲
NORFLOXACIN TEVA 400 mg, tablets
UTINOR 400 mg, tablets
U.S.A. and Puerto Rico: ▲
CHIBROXIN 3 mg/ml, 5 ml eye drops
NOROXIN 400 mg, 20 tablets
Page updated: December 21, 2010.