spironolactone: What is, what is used for, dose, side effects, brands

SPIRONOLACTONE

Indications and usage
Important information
Before taking
How to use
While taking
Side effects
Brands

List of brands containing spironolactone

This page contains list of brands of authorized pharmaceutical specialties of the active principle spironolactone in the countries listed below:

[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.

Indications and usage ▲

Spironolactone is in a group of drugs called diuretics. These are drugs that increase the removal of body fluids.

This medicine is used to reduce high blood pressure, swelling due to the accumulation of fluid (edema) that cause certain diseases of the kidney, liver or heart and for the treatment of heart failure in combination with other drugs.

It is also used in the diagnosis and treatment of diseases caused by an abnormally high production of the natural hormone aldosterone.

Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given spironolactone.

Other ingredients of available commercial presentations:

Besides the active ingredient spironolactone, the other components are calcium sulfate dihydrate, gluten corn starch, polyvidone, peppermint flavor and magnesium stearate. The tablet coating contains hydroxypropyl methylcellulose, polyethylene glycol and Opaspray M-1-7111 B (white). Some specialties contain lactose.

Warning:

The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.

Important information ▲

This medicine may contain lactose. If your doctor has told you that you have an intolerance to some sugars, contact him before taking it

Use in sportspeople:

This medicine contains a component that may establish an analytical result of doping control as positive.

Before taking the drug ▲

Do not use spironolactone

If you are allergic (hypersensitive) to spironolactone, to other similar medicines or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.

Allergy symptoms may include:

- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).

Nor you should take this medicine:

- If you have certain disorders of the kidney function (acute renal failure, a very impaired renal function, lack of arrival of urine to the bladder or anuria)
- If you have a high blood potassium level
- If you suffer from Addison's disease that produces a damage resulting in adrenocortical hormone deficiency.

Take special care with spironolactone

- If you have severe liver problems, including liver cirrhosis
- If you are diabetic
- If you have kidney or liver problems or if you are elderly, the use of spironolactone may alter blood levels of some electrolytes so your doctor will perform regular monitoring
- Spironolactone use together salt substitutes is not recommended because can cause severe poisoning.

During the treatment with this medicine, maybe your doctor may do periodic tests to control sodium levels in blood and thus predict the risk of adverse effects.

Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.

If in doubt, consult your doctor.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription

It may be necessary to change the dose, or in some cases, discontinue one treatment. This applies to all types of drugs, but especially for:

There are some medications which may interact with spironolactone:

- Drugs that may alter potassium levels in the blood (eg potassium-sparing diuretics)
- Medicines for pain and fever (eg Aspirin, antipyrine)
- Some anti-ulcer drug (eg carbenoxolone)
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Drugs that may alter the balance of electrolytes in the body (eg ammonium chloride, cholestyramine)
- Certain anti-inflammatory drugs (corticosteroids)
- Other medicines that lower blood pressure (antihypertensives),
- Alcohol, barbiturates, narcotics
- Drugs used in emergency situations to raise blood pressure (eg norepinephrine)
- Medicines to regulate heartbeat (eg digoxin)
- Lithium

Interference with laboratory tests:

This medicine may interfere with the results of some diagnostic tests. If you must undergo any test to assess levels of digoxin tell your doctor that you are taking spironolactone as it can alter the results.

Use with food and beverages

Avoid drinking too much alcohol while taking this medication because it may potentiate the hypotensive effect of spironolactone.

Special physiological situations

Pregnancy and lactation:

Always consult your doctor or pharmacist before taking any medicine during pregnancy or breastfeeding.

You should not take spironolactone if you are pregnant, you think you might be pregnant or are trying to become pregnant. Women of childbearing age should take appropriate contraceptive measures.

Do not take this medicine if you are breastfeeding your child.

Driving and using machines

Spironolactone may cause drowsiness and dizziness, especially when starting treatment. If you notice such effects, you should consult your doctor before performing these activities.

Do not use any tools or machines if your ability to use them is affected by this medicine.

How to use spironolactone ▲

Follow carefully instructions of use of spironolactone provided by your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.

The usual dose of spironolactone is 50 to 100 mg daily.

In the case of heart failure, the usual starting dose is 25 mg per day.

If necessary, your doctor may increase or decrease the dose to achieve that you need. Your doctor will adapt the dose at intervals of 2 weeks or more. The maximum dose of this medication is 400 mg a day.

In children, the dose can be given if the child is able to swallow tablets.

Spironolactone tablets can be taken at any time of day with or without food. However, you should try to take your tablet at the same time every day.

Your doctor will decide the duration of treatment with this medicine.

If you think the effect of the medicine is too strong or too weak, consult your doctor.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

While you take spironolactone ▲

If a doctor prescribes another medicine, tell you are taking spironolactone.

Check with your doctor regularly developments of disorder that motivates the use of spironolactone. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.

Do not restart treatment with spironolactone at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.

If you feel unwell during treatment with spironolactone, immediately consult your doctor.

If you take more than you should:

If you have taken an overdose of spironolactone tell your doctor immediately or go to the emergency room of the nearest hospital. Take the pack and the rest of unconsumed medicine.

If you forget to take spironolactone

If you forget to take a dose, take the next scheduled dose at the correct time. Do not take a double dose to make up for missed doses.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Side Effects of spironolactone ▲

Like all medicines, spironolactone can cause side effects although not everybody gets them.

The frequency of side effects is classified into:

Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data

The following side effects are important and if you suffer one of them require immediate action:

Sometimes, the patients have suffered electrolyte blood disturbances, which very rarely has resulted in a serious life-threatening illness (called hyperkalemia). If you have heart rhythm disturbances, tingling, muscular weakness, flaccid paralysis, and muscle spasms. If this occurs, stop taking this medicine and contact your doctor immediately

Common side effects:

- Malaise, fatigue, tiredness, headaches, erectile dysfunction, drowsiness
- excessive development of breasts in men (gynecomastia), changes in menstruation (irregularities, amenorrhea, postmenopausal bleeding)
- Diarrhea, nausea

Uncommon side effects:

- Skin disorders (rashes, spots), redness, urticaria, itching,
- Disturbances of blood electrolytes, as hypercalcemia (elevated blood calcium) or hyponatremia (decreased blood sodium),
- Cramps tingling (paraesthesia)
- Confusion
- Increased blood concentration of creatinine

Rare or very rare side effects:

- benign breast cysts chest pain
- Hair loss (alopecia) excessive hair growth (hypertrichosis)
- Dizziness incoordination of movements (ataxia)
- Changes in libido
- Acute renal failure
- Leucopenia (decreased number of white blood cells) , thrombocytopenia (decreased number of platelets in the blood)
- Disturbances of liver function

If you have any side effects, tell your doctor. He will decide what actions need to be taken

This list does not include all adverse reactions associated with the use of spironolactone, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.

If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.

If any of the side effects gets serious, tell your doctor or pharmacist.

List of brands containing spironolactone ▲

This page contains list of brands of authorized pharmaceutical specialties of the active principle spironolactone in the countries listed below:

[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]

Warning:

With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.

Australia: ▲

ALDACTONE 25 mg, 100 tablets
ALDACTONE 100 mg, 100 tablets
SPIRACTIN 25 mg, 100 tablets
SPIRACTIN 100 mg, 100 tablets

Brazil: ▲

ALDACTONE 25 mg, 30 tablets
ALDACTONE 50 mg, 30 tablets
ALDOSTERIN 100 mg, 16 tablets
ALDOSTERIN 25 mg, 20-30 tablets
ALDOSTERIN 50 mg, 30 tablets
DIACQUA 100 mg, 16 tablets
DIACQUA 25 mg, 10-30 tablets
DIACQUA 50 mg, 10-30 tablets
ESPIRONOLACTONA EMS 25 mg, 30 -60 tablets
ESPIRONOLACTONA EMS 50 mg, 30-60 tablets
ESPIRONOLACTONA EMS 100 mg, 16-30 tablets
ESPIRONOLACTONA GERMED 25 mg, 30 tablets
ESPIRONOLACTONA GERMED 50 mg, 30 tablets
ESPIRONOLACTONA GERMED 100 mg, 16-30 tablets
ESPIRONOLACTONA EUROFARMA 25 mg, 30 tablets
ESPIRONOLACTONA EUROFARMA 50 mg, 30 tablets
ESPIRONOLACTONA EUROFARMA 100 mg, 16 tablets
SPIROCTAN 25 mg, 30 tablets
SPIROCTAN 100 mg, 20-30-100 tablets

Canada: ▲

ALDACTONE 100 mg, 100 tablets
ALDACTONE 25 mg, 100 tablets
NTP-SPIRONOLACTONE 25 mg, 100 tablets
NTP-SPIRONOLACTONE 100 mg, 100 tablets
TEVA-SPIRONOLACTONE 25 mg, 100 tablets
TEVA-SPIRONOLACTONE 100 mg, 100 tablets

France: ▲

ALDACTONE 25 mg, divisible tablets
ALDACTONE 50 mg, divisible tablets
ALDACTONE 75 mg, divisible tablets
SPIROCTAN 50 mg, capsules
SPIROCTAN 75 mg, capsules
SPIRONOLACTONE ACTAVIS 25 mg, divisible tablets
SPIRONOLACTONE ARROW 25 mg, divisible tablets
SPIRONOLACTONE ARROW 50 mg, divisible tablets
SPIRONOLACTONE ARROW 75 mg, divisible tablets
SPIRONOLACTONE ARROW LAB 50 mg, divisible tablets
SPIRONOLACTONE ARROW LAB 75 mg, divisible tablets
SPIRONOLACTONE BIOGARAN 25 mg, divisible tablets
SPIRONOLACTONE BIOGARAN 50 mg, divisible tablets
SPIRONOLACTONE BIOGARAN 75 mg, divisible tablets
SPIRONOLACTONE CRISTERS 25 mg, divisible tablets
SPIRONOLACTONE CRISTERS 50 mg, divisible tablets
SPIRONOLACTONE CRISTERS 75 mg, divisible tablets
SPIRONOLACTONE EG 25 mg, divisible tablets
SPIRONOLACTONE EG 50 mg, divisible tablets
SPIRONOLACTONE EG 75 mg, divisible tablets
SPIRONOLACTONE MICROFINE RATIOPHARM 50 mg, divisible tablets
SPIRONOLACTONE MYLAN 25 mg, divisible tablets
SPIRONOLACTONE MYLAN 50 mg, divisible tablets
SPIRONOLACTONE MYLAN 75 mg, divisible tablets
SPIRONOLACTONE PFIZER 25 mg, divisible tablets
SPIRONOLACTONE PFIZER 50 mg, divisible tablets
SPIRONOLACTONE PFIZER 75 mg, divisible tablets
SPIRONOLACTONE RATIOPHARM 25 mg, divisible tablets
SPIRONOLACTONE RATIOPHARM 75 mg, divisible tablets
SPIRONOLACTONE RPG 50 mg, divisible tablets
SPIRONOLACTONE RPG 75 mg, divisible tablets
SPIRONOLACTONE SANDOZ 25 mg, divisible tablets
SPIRONOLACTONE SANDOZ 50 mg, divisible tablets
SPIRONOLACTONE SANDOZ 75 mg, divisible tablets
SPIRONOLACTONE TEVA 25 mg, divisible tablets
SPIRONOLACTONE TEVA 50 mg, divisible tablets
SPIRONOLACTONE TEVA 75 mg, divisible tablets
SPIRONOLACTONE ZENTIVA 25 mg, divisible tablets
SPIRONOLACTONE ZENTIVA 50 mg, divisible tablets
SPIRONOLACTONE ZENTIVA 75 mg, divisible tablets
SPIRONOLACTONE ZYDUS 25 mg, divisible tablets
SPIRONOLACTONE ZYDUS 50 mg, divisible tablets
SPIRONOLACTONE ZYDUS 75 mg, divisible tablets

Germany: ▲

ALDACTONE 25 mg, tablets
ALDACTONE 50 mg, tablets
ALDACTONE 100 mg, capsules
JENASPIRON 50 mg, tablets
JENASPIRON100 mg, tablets
OSYROL 50 mg, tablets
OSYROL 100 mg, tablets
SPIRO-CT 50 mg, tablets
SPIRO-CT 100 mg, tablets
SPIROBETA 50 mg, tablets
SPIROBETA 100 mg, tablets
SPIROGAMMA 50 mg, tablets
SPIROGAMMA 100 mg, tablets
SPIRONOLACTON-1A PPHARMA 50 mg, tablets
SPIRONOLACTON-1A PHARMA100 mg, tablets
SPIRONOLACTON HEUMANN 50 mg, tablets
SPIRONOLACTON HEUMANN 100 mg, tablets
SPIRONOLACTON AAA 50 mg, tablets
SPIRONOLACTON AAA 100 mg, tablets
SPIRONOLACTON AL 50 mg, tablets
SPIRONOLACTON AL 100 mg, tablets
SPIRONOLACTON ARISTO 50 mg, tablets
SPIRONOLACTON ARISTO 100 mg, tablets
SPIRONOLACTON DURA 50 mg, tablets
SPIRONOLACTON DURA 100 mg, tablets
SPIRONOLACTON HEXAL 50 mg, tablets
SPIRONOLACTON HEXAL 100 mg, tablets
SPIRONOLACTON-RATIOPHARM 50 mg, tablets
SPIRONOLACTON-RATIOPHARM 100 mg, tablets
SPIRONOLACTON SANDOZ 50 mg, tablets
SPIRONOLACTON SANDOZ 100 mg, tablets
SPIRONOLACTON STADA 50 mg, tablets
SPIRONOLACTON STADA 100 mg, tablets
VEROSPIRON T 25 mg, tablets

India: ▲

ALDACTONE 25 mg, tablets
ALDACTONE 50 mg, tablets
ALDACTONE 100 mg, tablets
SPILACTONE 50 mg, tablets

Italy: ▲

ALDACTONE 25 mg, 16 capsules
ALDACTONE 100 mg, 10 tablets
SPIROLANG 25 mg, 16 capsules
SPIROLANG 50 mg, 10 capsules
SPIROLANG 100 mg, 10 capsules
URACTONE 100 mg, 10 tablets

Japan: ▲

ALDACTONE-A 10% 1 g, fine gran
. ALDACTONE-A 25 mg, tablets
ALDACTONE A 50 mg, tablets
NOIDOUBLE . 25 mg, tablets
SPIRONOLACTONE CH. 25 mg, tablets
SPIRONOLACTONE CH. 50 mg, tablets
SPIRONOLACTONE NICHI-IKO. 25 mg, tablets
SPIRONOLACTONE NP. 25 mg, tablets
SPIRONOLACTONE TCK. 25 mg, tablets
SPIRONOLACTONE TEVA. 25 mg, tablets
SPIRONOLACTONE TOWA. 25 mg, tablets
SPIRONOLACTONE TSURUHARA. 25 mg, tablets
SPIRONOLACTONE YD. 25 mg, tablets
SPIRONOLACTONE YD. 50 mg, tablets

Mexico: ▲

ALDACTONE 100 mg, 30 tablets
ALDACTONE A 25 mg, 30 tablets
BIOLACTONA 25 mg, 20 & 25 tablets
ESPIRONOLACTONA BIORESEARCH 25 mg, 20 tablets
NOLASQUE 25 mg, 20, 30 & 100 tablets
NOLASQUE 100 mg, 30 & 100 tablets
VIVITAR 25 mg, 30 tablets
VIVITAR 100 mg, 30 tablets

Pakistan: ▲

ALDACTONE-A 25 mg, tablets
ALDACTONE 100 mg, tablets
DI-URATE 50 mg, tablets
DIUTON 100 mg, tablets

Spain: ▲

ALDACTONE 25 mg, 20-50 tablets
ALDACTONE 100 mg, 20 tablets
ESPIRONOLACTONA ALTER 25 mg, 20-50 tablets
ESPIRONOLACTONA ALTER 100 mg, 20 tablets
RESNEDAL 20 tablets
SPIROMETON 20-60 tablets

Turkey: ▲

ALDACTONE 25 mg, 20 tablets
ALDACTONE 100 mg, 16 tablets

United Kingdom: ▲

ALDACTONE 25 mg, 28 tablets
ALDACTONE 50 mg, 28 tablets
ALDACTONE 100 mg, 28 tablets
SPIRONOLACTONE ACCORD 25 mg, 28 tablets
SPIRONOLACTONE ACCORD 50 mg, 28 tablets
SPIRONOLACTONE ACCORD 100 mg, 28 tablets
SPIRONOLACTONE ACTAVIS 25 mg, 28 tablets
SPIRONOLACTONE ACTAVIS 50 mg, 28 tablets
SPIRONOLACTONE ACTAVIS 100 mg, 28 tablets
SPIRONOLACTONE KENT 100 mg, 28 tablets

U.S.A. and Puerto Rico: ▲

ALDACTONE 25 mg, 100 tablets
ALDACTONE 50 mg, 100 tablets
ALDACTONE 100 mg, 100 tablets
SPIRONOLACTONE ACTAVIS 25 mg, 100 tablets
SPIRONOLACTONE ACTAVIS 50 mg, 100 tablets
SPIRONOLACTONE ACTAVIS 100 mg, 100 tablets
SPIRONOLACTONE AMNEAL PHARMA 25 mg, 30, 50, 60 & 100 tablets
SPIRONOLACTONE AMNEAL PHARMA 50 mg, 30, 50, 60 & 100 tablets
SPIRONOLACTONE AMNEAL PHARMA 100 mg, 30, 50, 60 & 100 tablets
SPIRONOLACTONE GREENSTONE 25 mg, 100 tablets
SPIRONOLACTONE GREENSTONE 50 mg, 50 tablets
SPIRONOLACTONE GREENSTONE 100 mg, 50 tablets
SPIRONOLACTONE MCKESSON 50 mg, 100 tablets
SPIRONOLACTONE MAJOR PHARMA 25 mg, 100 tablets
SPIRONOLACTONE MAJOR PHARMA 50 mg, 50 tablets
SPIRONOLACTONE MAJOR PHARMA 100 mg, 50 tablets
SPIRONOLACTONE MED HEALTH PHARMA 25 mg, 30 & 50 tablets
SPIRONOLACTONE MED HEALTH PHARMA 50 mg, 30 tablets
SPIRONOLACTONE MED HEALTH PHARMA 100 mg, 10 & 30 tablets
SPIRONOLACTONE MUTUAL PHARMA 25 mg, 100 tablets
SPIRONOLACTONE MUTUAL PHARMA 50 mg, 30, 50, 60 &100 tablets
SPIRONOLACTONE MUTUAL PHARMA 100 mg, 30, 50, 60 & 100 tablets
SPIRONOLACTONE MYLAN 25 mg, 100 tablets
SPIRONOLACTONE MYLAN 50 mg, 30 &100 tablets
SPIRONOLACTONE MYLAN 100 mg, 100 tablets
SPIRONOLACTONE NCS HEALTHCARE OF KY 25 mg, 15, 30 & 31 tablets
SPIRONOLACTONE NCS HEALTHCARE OF KY 50 mg, 30 tablets
SPIRONOLACTONE NCS HEALTHCARE OF KY 100 mg, 30 tablets
SPIRONOLACTONE PHYSICIANS TOTAL CARE 25 mg, 50, 60, 90 &100 tablets
SPIRONOLACTONE PHYSICIANS TOTAL CARE 50 mg, 30, 60 & 100 tablets
SPIRONOLACTONE PHYSICIANS TOTAL CARE 100 mg, 10, 30, 60, 90 & 100 tablets
SPIRONOLACTONE QUALITEST 25 mg, 10, 30 & 100 tablets
SPIRONOLACTONE QUALITEST 50 mg, 10, 30 & 100 tablets
SPIRONOLACTONE QUALITEST 100 mg, 10, 30 & 100 tablets
SPIRONOLACTONE REBEL 25 mg, 30 tablets
SPIRONOLACTONE SANDOZ 25 mg, 100 tablets
SPIRONOLACTONE STAT FLORIDA DOH CENTRAL PHARM 25 mg, 30 tablets
SPIRONOLACTONE STAT FLORIDA DOH CENTRAL PHARM 100 mg, 30 tablets
SPIRONOLACTONE UDL 25 mg, 25, 30 & 100 tablets
SPIRONOLACTONE UDL 50 mg, 100 tablets
SPIRONOLACTONE UDL 100 mg, 100 tablets

Page updated: December 11, 2010.