Sulpiride is indicated in the treatment of:
- Psychopathological disorders (neurosis, depression, neurotic somatizations).
- Functional psychological disorders.
- Psychosomatic syndromes.
- Senile dementia
- Gastrointestinal somatizations
- Vertigo.
Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given sulpiride.
Other ingredients of available commercial presentations:
50 mg capsules:
The other ingredients are lactose monohydrate, methylcellulose, talc, magnesium stearate. Gelatin capsules contain titanium dioxide (E171).
50 mg tablets:
The other ingredients are corn starch, microcrystalline cellulose, lactose, talc, magnesium stearate, colloidal silica and sodium starch glycolate.
200 mg tablets
The other ingredients are lactose monohydrate, potato starch gluten, methylcellulose, colloidal silica, talc and magnesium stearate.
Oral solution
The other ingredients are sodium cyclamate, hydroxyethyl cellulose; Methyl para-hydroxybenzoate (E-216); Propyl para-hydroxybenzoate (E218); Citric acid monohydrate; Hydrochloric acid; Sorbic acid; Lemon essence and purified water. The measuring cup (15 ml) = 75 mg sulpiride.
Injectable solution
The other ingredients are sulfuric acid, sodium chloride and water for injections. A 2 ml ampoule contains 100 mg of sulpiride.
Warning:
The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.
Do not use sulpiride
If you are allergic (hypersensitive) to sulpiride or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.
Allergy symptoms may include:
- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).
Nor you should take this medicine:
- If you have a prolactin-dependent tumor (a hormone that stimulates milk secretion), e.g. pituitary gland prolactinomas and breast cancer.
- If you have a type of tumor called pheochromocytoma.
- If you are taking a drug for Parkinson's disease called levodopa.
- If you have bradycardia (heart beats more slowly), if you have heart rhythm disturbances or another major heart disease.
Take special care with sulpiride
- If the drug is administered to elderly, since there is a risk of sedation and decrease in blood pressure upon standing (orthostatic hypotension).
- If the drug is given to children, since sulpiride has not been thoroughly investigated in this age group.
- If you have kidney failure because you probably need a dose adjustment.
- If you have or have had epilepsy, since the class of drugs to which it belongs sulpiride may promote the development of seizures.
- If you have Parkinson's disease, as sulpiride is contraindicated, apart from exceptional cases, in patients taking antiparkinsonian medication.
- If you have unexplained fever and muscle stiffness, as it could be a neuroleptic malignant syndrome, a potentially fatal complication characterized by high body temperature, which may cause muscle rigidity and autonomic nervous system dysfunction.
If you have an elevated body temperature from an undiagnosed illness, should be discontinued the sulpiride administration.
This medicine may increase the risk of serious heart rhythm disturbances.
Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.
If in doubt, consult your doctor.
Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.
Especially, tell your doctor or pharmacist if you are taking:
- Levodopa.
- antiarrhythmic agents such as quinidine, disopyramide, amiodarone y sotalol.
- Other medicines such as cisapride, thioridazine, intravenous erythromycin, vincamine IV, halofantrine, pentamidine, sparfloxacin.
- Medications that induce bradycardia (slowing of heart rate) such as diltiazem and verapamil, clonidine, guanfacine o digitalis.
- Medications that induce decreased levels of potassium and magnesium.
- CNS depressants including narcotics, anesthetics, painkillers, H1 antihistamines, sedatives, barbiturates, benzodiazepines and other anxiolytic drugs.
- lithium salts.
- Sucralfate.
- Antacids.
- drugs for high blood pressure.
Note that these warnings also include drugs which can be taken before or after sulpiride.
Use with food and beverages
Since alcohol enhances the sedative effect of sulpiride, it is not recommended drinking alcoholic beverages and other medications containing alcohol in its composition while taking this medicine.
Should not drink grapefruit juice during treatment with sulpiride.
Sulpiride should be taken preferably before meals.
Consult your doctor or pharmacist before taking any medicine.
Special physiological situations
Pregnancy and lactation
The use of this medicine is not recommended during pregnancy.
This medicine is excreted in breast milk, so breast-feeding is not recommended during treatment with sulpiride.
always consult your doctor or pharmacist before taking any medicine during pregnancy or lactation.
Use in children
There are not enough studies to support the use of sulpiride in children, so it is not recommended.
Use in elderly
The dosage of this medicine should be adapted to the conditions of the elderly patient. In any case, it should be used with caution.
Driving and using machines
Sulpiride may affect reaction time and, consequently, the ability to drive vehicles or operate machinery. So, it is recommended a special caution, checking previously if sulpiride affects your abilities for driving or operating machinery.
Consult your doctor or pharmacist before taking any medicine.
Follow carefully instructions of use of sulpiride provided by your doctor. Consult your doctor or pharmacist when in doubt. Follow the instructions of the physician in preference to those given in this website, which may be different. Ask your doctor to explain any aspect that you do not understand, contained in the instruction leaflet that comes with the medicine.
Your doctor will determine the appropriate dose and duration of treatment; Do not stop taking before or prolong more than prescribed by your doctor.
The duration of this treatment is limited.
Your doctor will indicate the duration of the treatment and how to increase the dose. Do not stop treatment abruptly since may reappear symptoms of your illness.
The dose is different depending on the illness you suffer:
As a rule, the usual dose is:
Adults:
The recommended dose is 3 to 6 capsules per day (50 mg). In vertigo, it can be increased up to 9 capsules per day. Divide the whole dose into three doses throughout the day, preferably administered prior to the meals.
If you use the oral solution: 2-4 dosing cups (150-300 mg) per day.
Sulpiride should be taken at least two hours before antacids and sucralfate.
Kidney failure:
In the case of renal impairment, dosage should be adapted to the kidney functional ability for removing. Your doctor will adjust the dose according to the following scheme:
- Creatinine clearance 30-60 ml/min: administer 50-70% usual dose
- Creatinine clearance 10-30 ml/min: administer 35-50% usual dose
- Creatinine clearance less than 10 ml/min: administer a maximum 35% usual dose.
Elderly:
Elderly patients may have higher sulpiride blood level than expected. Therefore, these patients need a lower starting dose and a more gradual titration than young adults.
If you think the effect of the medicine is too strong or too weak, consult your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
If a doctor prescribes another medicine, tell you are taking sulpiride.
Check with your doctor regularly developments of disorder that motivates the use of sulpiride. Maybe there is some reason that prevented you properly receive the indicated doses and induce your doctor to erroneous conclusions about treatment.
Do not restart treatment with sulpiride at your own risk without first talking to your doctor, nor encourage its use by another person, even if have the same symptoms you have. Nor is it advisable to interrupt or reduce the dose without considering the opinion of your doctor.
If you feel unwell during treatment with sulpiride, immediately consult your doctor.
If you take more than you should:
In the case of overdose, spasms of the muscles of the face, neck and tongue may occur. Some patients may develop parkinsonian manifestations (tremor, stiffness) life-threatening and even coma.
There is no specific antidote to sulpiride; treatment is only symptomatic and hemodialysis is not effective in eliminating the drug. In the case of overdose, must be started appropriate support measures, recommending close monitoring of vital functions, controlling cardiac function until the patient recovers.
In the case of overdose or accidental ingestion, consult your doctor or pharmacist immediately or call the National Poisons Information Service in your country. If you have taken a sulpiride overdose, go to the emergency department of the nearest hospital. Take the container with you, even if it is empty.
If you forget to take sulpiride
Do not take a double dose to make up for a forgotten dose.
If you stop taking sulpiride
It is not recommended abrupt cessation of treatment with sulpiride unless your doctor tells you so.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Like all medicines, sulpiride can cause side effects although not everybody gets them.
The frequency of side effects is classified into:
Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data
Heart disorders:
- Low blood pressure upon standing.
- Very rare : problems in the conduction of the electrical impulse of the heart and torsade de pointes.
Hormonal disorders:
- Increased levels of prolactin.
General disorders:
- Like all neuroleptics, neuroleptic malignant syndrome, a potentially fatal complication.
- Weight gain.
Liver disorders:
- Very rare: increase in liver enzymes.
Nervous System Disorders:
- Sedation or drowsiness.
- Extrapyramidal symptoms and related disorders.
- Parkinsonism and related symptoms: tremor, increased muscle tone, slowness of movement, increased salivation
- slowness of movement and decreased muscle tone (spasmodic torticollis, decreased tone in the craniofacial region, pressure exerted on the teeth involuntarily).
- Inability to sit or to remain sitting (akathisia). These symptoms are usually reversible if administered antiparkinsonian medicines.
- Tardive dyskinesia (characterized by rhythmic, involuntary movements primarily of the tongue and/or face), as happens with all neuroleptics, after administration for more than 3 months. The antiparkinsonian medication is ineffective or may aggravate the symptoms.
- Very rare: seizures
Disorders of the reproductive system and breast. Disorders associated with increased prolactin levels:
- Abnormal secretion of breast milk (outside of pregnancy period).
- Ther absence of menstruation in a fertile woman (amenorrhea).
- Enlarged breasts in men (gynecomastia).
- Enlarged breasts in women.
- Breast pain.
- Orgasmic dysfunction.
- Impotence.
Skin and subcutaneous tissues disorders:
- Very rare: Maculopapular rashes (with spots and hives).
This list does not include all adverse reactions associated with the use of sulpiride, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.
If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.
If any of the side effects gets serious, tell your doctor or pharmacist.
This page contains list of brands of authorized pharmaceutical specialties of the active principle sulpiride in the countries listed below:
[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]
Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.
Warning:
With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.
Australia: ▲
N/A
Brazil: ▲
DOGMATIL 50 mg, 20 capsules
DOGMATIL 20 mg/ml, 30 ml oral drops (1 mg/drop)
DOGMATIL 200 mg, 20 tablets
EQUILID 50 mg, 20 capsules
EQUILID 200 mg, 20 tablets
Canada: ▲
N/A
France: ▲
DOGMATIL 5 mg/ml , oral solution
DOGMATIL 50 mg/ml, injectable solution injectable
DOGMATIL 200 mg, divisible tablets
DOGMATIL 50 mg, capsules
SULPIRIDE MYLAN 200 mg, divisible tablets
SULPIRIDE MYLAN 50 mg, capsules
SULPIRIDE SANDOZ 50 mg, capsules
SULPIRIDE TEVA 200 mg, divisible tablets
SULPIRIDE TEVA 50 mg, capsules
SULPIRIDE ZENTIVA 200 mg, divisible tablets
SULPIRIDE ZENTIVA 50 mg, capsules
SYNEDIL 5 mg/ml , oral solution
SYNEDIL 50 mg, capsules
SYNEDIL FORT 200 mg, tablets
Germany: ▲
DOGMATIL FORTE 200 mg, tablets
DOGMATIL 50 mg/ml, injectable solution
DOGMATIL 50 mg, capsules
DOGMATIL 5 mg/ml, oral solution
MERESA FORTE 200 mg, tablets
MERESASUL 50 mg, capsules
SULPIRID AL 200 mg, tablets
SULPIRID AL 50 mg, tablets
SULPIRID BETA 200 mg, tablets
SULPIRID BETA 50 mg, capsules
SULPIRID HEXAL 100 mg, tablets
SULPIRID HEXAL 200 mg, tablets
SULPIRID HEXAL 50 mg, capsules
SULPIRID REAL 200 mg, tablets
SULPIRID REAL 50 mg, capsules
SULPIRID RPH 200 mg, tablets
SULPIRID RPH 50 mg, capsules
SULPIRID SANDOZ 200 mg, tablets
SULPIRID SANDOZ 50 mg, tablets
SULPIRID STADA 200 mg, tablets
SULPIRID STADA 50 mg, tablets
SULPIRID-1 A PHARMA 100 mg, tablets
SULPIRID-1 A PHARMA 200 mg, tablets
SULPIRID-1 A PHARMA 50 mg, capsules
SULPIRID-CT 200 mg mg, tablets
SULPIRID-CT 50 mg, tablets
SULPIRID-HORMOSAN 200 mg, tablets
SULPIRID-HORMOSAN 50 mg, capsules
SULPIRID-NEURAXPHARM 100 mg, tablets
SULPIRID-NEURAXPHARM 200 mg, tablets
SULPIRID-NEURAXPHARM 50 mg, tablets
SULPIRID-RATIOPHARM 200 mg, tablets
SULPIRID-RATIOPHARM 50 mg, tablets
SULPIRID-TEVA 50 mg, capsules
SULPIVERT 50 mg, capsules
SULPIVERT 100 mg, tablets
SULPIVERT FORTE 200 mg, tablets
VERTIGO-MERESA 200 mg, tablets
VERTIGO-MERESA 50 mg, capsules
VERTIGO-NEOGAMMA 100 mg, tablets
VERTIGO-NEOGAMMA 50 mg, tablets
VERTIGO-NEOGAMMA FORTE 200 mg, tablets
India: ▲
N/A
Italy: ▲
CHAMPIONYL 50 mg, 30 capsules
CHAMPIONYL 50 mg/ml, injectable solution
CHAMPIONYL 200 mg, 15 tablets
DOBREN 50 mg, 30 tablets
DOBREN 100 mg, 24 tablets
DOBREN 200 mg, 20 tablets
EQUILID 200 mg, 20 tablets
Japan: ▲
ABILIT 100 mg, tablets
ABILIT 200 mg, tablets
ABILIT 50 mg, capsules
ABILIT 50 mg, tablets
ABILIT 1 g, Fine Gran. 10%
ABILIT 1 g, Fine Gran. 50%
DOGMATYL 100 mg, tablets
DOGMATYL 200 mg, tablets
DOGMATYL 50 mg, capsules
DOGMATYL 50 mg, tablets
DOGMATYL 1 g, Fine Gran. 10%
DOGMATYL 1 g, Fine Gran. 50%
MIRADOL 100 mg, tablets
MIRADOL 200 mg, tablets
MIRADOL 50 mg, capsules
MIRADOL 50 mg, tablets
MIRADOL 1 g, Fine Gran. 10%
MIRADOL 1 g, Fine Gran. 50%
SULPIRIDE AMEL 1 g, Fine Gran. 10%
SULPIRIDE AMEL 100 mg, tablets
SULPIRIDE AMEL 200 mg, tablets
SULPIRIDE AMEL 50 mg, tablets
SULPIRIDE AMEL 1 g, Fine Gran. 50%
SULPIRIDE CH 50 mg, tablets
SULPIRIDE ISEI 50 mg, capsules
SULPIRIDE SAWAI 100 mg, tablets
SULPIRIDE SAWAI 200 mg, tablets
SULPIRIDE SAWAI 50 mg, tablets
SULPIRIDE TCK 50 mg, capsules
SULPIRIDE TCK 50 mg, tablets
SULPIRIDE TOWA 100 mg, tablets
SULPIRIDE TOWA 200 mg, tablets
SULPIRIDE TOWA 50 mg, capsules
SULPIRIDE TYK 100 mg, tablets
SULPIRIDE TYK 200 mg, tablets
SULPIRIDE TYK 50 mg, tablet
Mexico: ▲
EKILID 50 mg, 40 capsules
PONTIRIDE 50 mg, 50 tablets
PONTIRIDE 200 mg, 20 tablets
RIMASTINE 50 mg, 30 tablets
RIMASTINE 100 mg, 20 tablets
RIMASTINE 200 mg, 20 tablets
Pakistan: ▲
LEVOMA 25 mg, tablets
LEVOMA 50 mg, tablets
SULPADE 100 mg, tablets
Spain: ▲
DIGTON FORTE 200 mg, 12 tablets
DIGTON 50 mg, 30 tablets
DOGMATIL 50 mg, 30 capsules
DOGMATIL 25 mg/5 ml, 200 ml oral solution
DOGMATIL FUERTE 200 mg, 12 and 36 tablets
DOGMATIL 100 mg/2 ml, injectable solution
GUASTIL 25 mg/5 ml, 200 ml oral solution
GUASTIL 50 mg, 30 capsules
PSICOCEN 50 mg, 30 capsules
TEPAVIL 50 mg, 20 tablets
Turkey: ▲
DOGMATIL 200 mg, 24 tablets
MERESA 100 mg/3 ml, injectable solution
MERESA 50 mg, 30 capsules
MERESA FORT 200 mg, 24 tablets
SULPIR 50 mg, 30 capsules
ZEPRID 50 mg, 30 capsules
ZEPRID 100 mg/3 ml, injectable solution
ZEPRID 200 mg, 12-24 capsules
ZEPRID 200 mg, 48 tablets
ZEPRID ORAL 5 mg/ml, 200 ml oral solution
United Kingdom: ▲
DOLMATIL 200 mg, 100 tablets
DOLMATIL 400 mg, 100 tablets
SULPIRIDE AAH PHARMA 200 mg, 30 tablets
SULPIRIDE AAH PHARMA 400 mg, 30 tablets
SULPIRIDE ALLIANCE HEALTHCARE 200 mg, 30 tablets
SULPIRIDE ALLIANCE HEALTHCARE 400 mg, 30 tablets
SULPIRIDE GENERICS 200 mg, 30 tablets
SULPIRIDE KENT PHARMA 200 mg, 30 tablets
SULPIRIDE KENT PHARMA 400 mg, 30 tablets
SULPIRIDE TEVA 200 mg, 30 tablets
SULPIRIDE WOCKHARDT 200 mg, 30 tablets
SULPIRIDE WOCKHARDT 400 mg, 30 tablets
SULPOR 40 mg/ml, 150 ml oral solution
U.S.A. and Puerto Rico: ▲
ND
Page updated: December 13, 2010.