Tizanidine belongs to a group of drugs called muscle relaxants. It is indicated for the treatment of muscle disorders associated with muscle spasm, such as:
- Musculoskeletal disorders of the spine, such as back pain, cervical or dorsal sprains, torticollis, etc. .
- musculoskeletal surgeries such as disc herniation intervention,
- Chronic inflammatory diseases (shoulder, hip, elbow),
- Neurological disorders involving muscle spasm: multiple sclerosis, chronic myelopathy, degenerative diseases of the bone marrow, cerebral vascular accidents stroke), cerebral palsy etc.
Medizzine recommends consulting your doctor if you are unsure (or you do not know) why you have been given tizanidine.
Other ingredients of available commercial presentations:
Tablets:
Each tablet contains 2 mg tizanidine. The other tablet components are lactose, microcrystalline cellulose, stearic acid and silica colloidal anhydrous.
Capsules:
In addition to 2, 4 or 6 mg tizanidine, these presentations contain lactose, ferrous-ferric oxide, silicon dioxide, gelatin, methyl cellulose, microcrystalline cellulose, potassium hydroxide, propylene glycol, red ferric oxide, shellac, talc, titanium dioxide and yellow ferric oxide.
Warning:
The composition of the various presentations may vary from one country to another. We recommend you consult the information provided by your local supplier.
Do not use tizanidine
If you are allergic (hypersensitive) to tizanidine or any of the other ingredients of the medicinal product prescribed to you. If you think may be allergic, ask your doctor.
Allergy symptoms may include:
- Asthma attacks with shortness of breath, audible wheezing or rapid breathing.
- More or less sudden swelling of the face, lips, tongue or elsewhere in the body. It is especially critical if it affects the vocal cords.
- Hives, itching, rash
- Anaphylactic shock (loss of consciousness, paleness, sweating, etc.).
Nor you should take this medicine:
- If you are taking fluvoxamine, an antidepressant drug
- If you are taking ciprofloxacin, an antibiotic to treat certain infections.
Take special care with tizanidine
- If you have kidney or liver failure, as your doctor may need to adjust the dose of tizanidine
- If you are taking more than 12 mg tizanidine (6 tablets) and note that you have nausea, fatigue and/or loss of appetite, contact your doctor since he may deem necessary to perform analysis periodically to monitor the proper functioning of your liver
- If you are taking antihypertensive medications at the same time as tizanidine, may result in lowered blood pressure, especially when you stand or sit up from the bed (orthostatic hypotension). This medicine can lead to alarming symptoms such as fainting, loss of consciousness and circulatory collapse, caused by the decreased blood pressure, even in patients not taking antihypertensive
- Do not change the dose or stop taking tizanidine without consulting your doctor.
- If you are taking oral contraceptives, you should tell your doctor, who should evaluate possible adjustments of the tizanidine dose since the contraceptives may increase the effects of this muscle relaxant.
Remember that your doctor has prescribed this medicine only for you. Never give it to someone else.
If in doubt, consult your doctor.
Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including herbal products or drugs obtained without a prescription.
Especially:
- The aforementioned fluvoxamine and ciprofloxacin (contraindicated)
- Antiarrhythmic drugs (used to treat heart rhythm disorders),
- Cimetidine, an antiulcer drug similar to ranitidine or famotidine,
- Fluoroquinolones, such as ciprofloxacin, levofloxacin, norfloxacin, etc., used to treat certain infections),
- Rofecoxib, an anti-inflammatory drug,
- Oral contraceptives,
- Ticlopidine (a drug used to prevent brain thromboembolic events),
- Medicines for high blood pressure, including diuretics, since tizanidine may enhance their effects,
- Powerful painkillers and sedatives. Tizanidine can enhance its effects.
If you are in any of these cases or are unsure, consult your doctor before starting to use tizanidine.
Use with food and beverages
Alcohol may increase the sedative effects of tizanidine so you are advised to abstain from alcohol while taking this medication.
Consult your doctor or pharmacist before taking any medicine.
Special physiological situations
Pregnancy and lactation:
Always consult your doctor or pharmacist before taking any medicine during pregnancy or breastfeeding.
Tizanidine is not recommended for use during pregnancy or breast-feeding.
Children:
Not recommended.
Driving and using machines
This medicine may make you feel sleepy or dizzy, have a cold sweat or perceive flashes, so you should not drive or operate dangerous machinery while taking.
Consult your doctor or pharmacist before taking any medicine.
Like all medicines, tizanidine can cause side effects although not everybody gets them.
The frequency of side effects is classified into:
Very common: affect 1 out of 1-10 patients
Common: affect 1 out of 10-100 patients
Uncommon: affect 1 out of 100-1.000 patients
Rare: affect 1 out of 1.000-10.000 patients
Very Rare: affect less than 1 in 10,000 patients
Incidence not known: Can not be established the true incidence from the available data
Common side effects
- Nervous system disorders: Drowsiness, dizziness.
- Cardiovascular disorders: Arterial hypotension, bradycardia (slowing of the pulse)
- Digestive disorders: Dry mouth.
Rare side effects
- General disorders: Fatigue, muscular weakness
- Psychiatric disorders: Hallucinations, sleep disorders, including insomnia
- Digestive and liver disorders: Nausea, gastrointestinal disturbances, transient increase in transaminases
Very rare side effects
- Liver disorders: acute hepatitis, liver failure
This list does not include all adverse reactions associated with the use of tizanidine, both well established as those that are under consideration or confirmation. In case you feel unwell, should immediately consult with the doctor who prescribed this medicine.
If you notice any side effects not listed in this website or in the leaflet accompanying the package, ask your doctor or pharmacist.
If any of the side effects gets serious, tell your doctor or pharmacist.
This page contains list of brands of authorized pharmaceutical specialties of the active principle tizanidine in the countries listed below:
[ Australia] [ Brazil] [ Canada] [ France] [ Germany] [ India] [ Italy] [ Japan] [ Mexico] [ Pakistan] [ Puerto Rico] [ Spain] [ Turkey] [ United Kingdom] [ U.S.A]
Given the nature of the pharmaceutical market, some specialties may be unavailable, have been removed from the pharmaceutical market or have changed its name. So that, in no case can take decisions based on the information contained in the page. MEDIZZINE is not responsible for any damage arising from the information provided, which may be incomplete or outdated.
Warning:
With exceptions expressly indicated, these lists do not include active principle associations with other drugs or clinical use containers.
Australia: ▲
N/A
Brazil: ▲
SIRDALUD 2 mg, 30 tablets
TIZANIDINA RANBAXY 2 mg, 30 tablets
Canada: ▲
APO-TIZANIDINE 4 mg, 100 tablets
MYLAN-TIZANIDINE 4 mg, 150 tablets
PAL-TIZANIDINE 4 mg, 100 tablets
France: ▲
N/A
Germany: ▲
SIRDALUP 2 mg, tablets
SIRDALUP 4 mg, tablets
SIRDALUP 6 mg, tablets
TIZANIDIN-TEVA 2 mg, tablets
TIZANIDIN-TEVA 4 mg, tablets
TIZANIDIN-TEVA 6 mg, tablets
India: ▲
ARZAN 2 mg, tablets
SIRDALUD 2 mg, tablets
SIRDALUD 4 mg, tablets
SIRDALUD 6 mg, tablets
TIDIRED 2 mg, tablets
TIZAN 2 mg, tablets
TIZAN 4 mg, tablets
TIZAN SR 6 mg, tablets
TIZONEC 2 mg, tablets
TIZOXX 2 mg, tablets
TIZPA 2 mg, tablets
TROMAZINE, tablets
VALERON, tablets
Italy: ▲
SIRDALUD 2 mg, 15-20 tablets
SIRDALUD 4 mg, 30 tablets
SIRDALUD 6 mg, 30 tablets
Japan: ▲
GIBONZ 1 mg, tablets
MOTONALIN 1 mg, tablets
TERNELIN 0.2%, 1 g gran
TERNELIN 1 mg, tablets
TIZANELIN 1 mg, tablets
TIZANIDINE AMEL 1 mg, tablets
TIZANIDINE JG 1 mg, tablets
TIZANIDINE NICHI-IKO 0.2%, 1 g gran
TIZANIDINE NICHI-IKO 1 mg, tablets
TIZANIDINE SAWAI 1 mg, tablets
TIZANIDINE TEVA 1 mg, tablets
TIZANIDINE TOWA 1 mg, tablets
TIZANIDINE TSURUHARA 1 mg, tablets
Mexico: ▲
SIRDALUD 2 mg, 20 tablets
SIRDALUD 6 mg, 10 capsules
Pakistan: ▲
AGILE 2 mg, tablets
AGILE FORTE 4 mg, tablets
AGILE SR 6 mg, capsules
ANALAR 2 mg, tablets
ARCOZID 2 mg, tablets
AZANID 2 mg, tablets
BIONERGICS 2 mg, tablets
COLRIL 4 mg, capsules
D-TONE 2 mg, tablets
FERNOR 2-4 mg, tablets
FERNOR SR 6 mg, tablets
KADIN 2 mg, tablets
KROMIS 2 mg, tablets
LENTIL 2 mg, tablets
LINTIZ 2-4 mg, tablets
MAKRELEX 2-4 mg, tablets
MAXLAX 2-4 mg, tablets
MICNIC 2-4 mg, tablets
MIZENAX 2 mg, tablets
MOLLUSCUS 2 mg, tablets
MOVAX 2-4 mg, tablets
MOVCOLM 2 mg, tablets
MOVE-EASE 2-4 mg, tablets
MR-X 4 mg, tablets
MUDINE 2 mg, tablets
MURAL 2-4 mg, tablets
MUREX 2 mg, tablets
MUSIDIN 2-4 mg, tablets
MUSLEX 2 mg, tablets
MUSNIDE 2 mg, tablets
MUSREL 2-4 mg, tablets
MUTIN 2 mg, tablets
MYLEX 2-4 mg, tablets
MYLIFAM 2 mg, tablets
MYODINE 2-4 mg, tablets
MYZAN 2-4 mg, tablets
NAZEDEN 2 mg, tablets
NEUTIZE 2-4 mg, tablets
NIMRELEX 2 mg, tablets
NYER 2 mg, tablets
ORTIZIDINE 2 mg, tablets
REDEEM 2 mg, tablets
RELAXADINE 2 mg, tablets
RELAXAMED 2 mg, tablets
RELAXIT 2 mg, tablets
REXANT 2 mg, tablets
SKELGESIC 2 mg, tablets
SKELWIN 2 mg, tablets
SKETEEZ 2 mg, tablets
SONETA 2 mg, tablets
SPASFREE 2 mg, tablets
SPASTIZ 2 mg, tablets
STRIVE 2 mg, tablets
SWANZID 2-4 mg, tablets
T-LEX 2 mg, tablets
TAIXA 4 mg, tablets
TANAVAX 4 mg, tablets
TANIN 2 mg, tablets
TANZIC 2 mg, tablets
TAZADIN 2-4 mg, tablets
TAZALEX 4 mg, tablets
TEMEL 2 mg, tablets
TERLADIN 2 mg, tablets
TERLAX 2-4 mg, tablets
TERNELIN 2-4 mg, tablets
TIGESIC 2 mg, tablets
TILAXIN 4 mg, tablets
TINADINE 2 mg, tablets
TINIC 2 mg, tablets
TINIC 4 mg, tablets
TINIZE 2 mg, tablets
TINIZE 6 mg, capsules
TINZA 2-4 mg, tablets
TIZADIN 2 mg, tablets
TIZAN 2 mg, capsules
TIZANAFLEX 2 mg, tablets
TIZANIADVAN 2 mg, tablets
TIZED 4 mg, tablets
TIZENAX 4 mg, tablets
TIZENEDAL 2 mg, tablets
TIZIGOOD 2-4 mg, tablets
TIZILEX 2-4 mg, tablets
TIZMIN 2 mg, tablets
TIZOCIN 2 mg, tablets
TIZODINE 2 mg, tablets
TIZOM 2 mg, tablets
TIZOREL 2-4 mg, tablets
TIZPA 2-4 mg, tablets
TONSIC 2 mg, tablets
TRAJIN 2 mg, tablets
TRANSDIN 2 mg, tablets
TRIZADINE 2 mg, tablets
TYZAN 2 mg, tablets
UNIXIDINE 2 mg, tablets
X-TANS 4 mg, tablets
XANDI 1 mg, tablets
ZADIN 2-4 mg, tablets
ZADINE 2 mg, tablets
ZANDIC 2-4 mg, tablets
ZANDIN 2 mg, tablets
ZANIDINE 2 mg, tablets
ZANIFLEX 2 mg, tablets
ZANTID 2-4 mg, tablets
ZANTID 4 mg, tablets
ZINAD 2 mg, tablets
ZITA 2-4 mg, tablets
Spain: ▲
SIRDALUD 2 mg, 30 tablets
SIRDALUD 4 mg, 30 tablets
Turkey: ▲
DEVALUD 2 mg, 30 tablets
DEVALUD 4 mg, 30 tablets
SIRDALUD 2 mg, 30 tablets
SIRDALUD 6 mg, 10 capsules
United Kingdom: ▲
TIZANIDINE AAH PHARMA 2 mg, tablets
TIZANIDINE AAH PHARMA 4 mg, tablets
TIZANIDINE ACTAVIS 2 mg, tablets
TIZANIDINE ACTAVIS 4 mg, tablets
TIZANIDINE ALLIANCE HEALTHCARE 2 mg, tablets
TIZANIDINE ALLIANCE HEALTHCARE 4 mg, tablets
TIZANIDINE GENERICS 2 mg, tablets
TIZANIDINE GENERICS 4 mg, tablets
TIZANIDINE TEVA 2 mg, tablets
TIZANIDINE TEVA 4 mg, tablets
ZANAFLEX 4 mg, tablets
U.S.A. and Puerto Rico: ▲
COMFORT PAC WITH TIZANIDINE PD-RX PHARMA 4 mg, 30 tablets
TIZANIDINE ACTAVIS 2 mg, 150 tablets
TIZANIDINE ACTAVIS 4 mg, 150 tablets
TIZANIDINE AIDAREX 2 mg, 10-120 tablets
TIZANIDINE AIDAREX 4 mg, 10-120 tablets
TIZANIDINE ALPHAPHARM 2 mg, 150 tablets
TIZANIDINE ALPHAPHARM 4 mg, 150 tablets
TIZANIDINE ALTURA 2 mg, 30-120 tablets
TIZANIDINE AMERICAN HEALTH PACK 2 mg, 30 tablets
TIZANIDINE AMERICAN HEALTH PACK 4 mg, 100 tablets
TIZANIDINE APHENA PHARMA 2 mg, tablets
TIZANIDINE APHENA PHARMA 4 mg, tablets
TIZANIDINE APOTEX 2 mg, 100 and 150 tablets
TIZANIDINE APOTEX 2 mg, 30 and 150 capsules
TIZANIDINE APOTEX 4 mg, 100 and 150 tablets
TIZANIDINE APOTEX 4 mg, 30 and 150 capsules
TIZANIDINE APOTEX 6 mg, 30 and 150 capsules
TIZANIDINE AVKARE 2 mg, 150 capsules
TIZANIDINE AVKARE 4 mg, 150 capsules
TIZANIDINE AVKARE 6 mg, 150 capsules
TIZANIDINE BLENHEIM PHARMACAL 4 mg, 20-180 tablets
TIZANIDINE BRYANT RANCH PREPACK 2 mg, 21-120 tablets
TIZANIDINE BRYANT RANCH PREPACK 4 mg, 20-140 tablets
TIZANIDINE BRYANT RANCH PREPACK 6 mg, 30, 60 and 90 capsules
TIZANIDINE CARACO 2 mg, 30, 100 and 150 tablets
TIZANIDINE CARACO 4 mg, 30, 100 and 150 tablets
TIZANIDINE CARDINAL HEALTH 2 mg, 10 and 150 tablets
TIZANIDINE CARDINAL HEALTH 4 mg, 10 and 30 tablets
TIZANIDINE CLINICAL SOLUTIONS 2 mg, 30, 60 and 90 tablets
TIZANIDINE CLINICAL SOLUTIONS 4 mg, 30-120 tablets
TIZANIDINE CLINICAL SOLUTONS 2 mg, 30 and 90 capsules
TIZANIDINE COREPHARMA 2 mg, 150 tablets
TIZANIDINE COREPHARMA 4 mg, 150 tablets
TIZANIDINE DIRECT RX 2 mg, 30, 60 and 90 tablets
TIZANIDINE DIRECT RX 4 mg, 30, 60, 90 and 120 tablets
TIZANIDINE DISPENSING SOLUTIONS 4 mg, 60 tablets
TIZANIDINE DR REDDY'S 2 mg, 30 and 150 tablets
TIZANIDINE DR REDDY'S 2 mg, 30 and 150 tablets
TIZANIDINE EON 2 mg, 150 tablets
TIZANIDINE EON 4 mg, 150 tablets
TIZANIDINE GOLDEN STATE MED SUPP 2 mg, 150 tablets
TIZANIDINE GOLDEN STATE MED SUPP 4 mg, 150 tablets
TIZANIDINE HJ HARKINS 2 mg, 20-150 tablets
TIZANIDINE HJ HARKINS 4 mg, 20-150 tablets
TIZANIDINE KELTMANN PHARMA 2 mg, 30 and 90 tablets
TIZANIDINE KELTMANN PHARMA 4 mg, 10-90 tablets
TIZANIDINE LAKE ERIE 2 mg, 30-180 tablets
TIZANIDINE LAKE ERIE 4 mg, 28-120 tablets
TIZANIDINE MAJOR 4 mg, 100 tablets
TIZANIDINE MCKESSON 4 mg, 30 tablets
TIZANIDINE MEDSOURCE PHARMA 2 mg, 30-120 tablets
TIZANIDINE MEDSOURCE PHARMA 4 mg, 30-120 tablets
TIZANIDINE MYLAN 2 mg, 100 and 150 tablets
TIZANIDINE MYLAN 2 mg, 150 capsules
TIZANIDINE MYLAN 4 mg, 100 and 150 tablets
TIZANIDINE MYLAN 4 mg, 150 capsules
TIZANIDINE MYLAN 6 mg, 150 capsules
TIZANIDINE NCS HEALTHCARE OF KY 2 mg, 30 tablets
TIZANIDINE NCS HEALTHCARE OF KY 4 mg, 30 tablets
TIZANIDINE NEW HORIZON 4 mg, 30 tablets
TIZANIDINE PD-RX 2 mg, 12, 30 and 60 tablets
TIZANIDINE PD-RX 4 mg, 15-90 tablets
TIZANIDINE PD-RX 4 mg, 20-90 tablets
TIZANIDINE PHYSICIANS TOTAL CARE 2 mg, 30-150 tablets
TIZANIDINE PHYSICIANS TOTAL CARE 4 mg, 20-270 tablets
TIZANIDINE PREFERRED PHARMA 2 mg, 30-120 tablets
TIZANIDINE PREFERRED PHARMA 4 mg, 30-120 tablets
TIZANIDINE PROFICIENT 4 mg, 30 and 60 tablets
TIZANIDINE REBEL 2 mg, 28-180 tablets
TIZANIDINE REBEL 4 mg, 14-120 tablets
TIZANIDINE REMEDYREPACK 2 mg, 30 tablets
TIZANIDINE REMEDYREPACK 4 mg, 15 and 30 tablets
TIZANIDINE STAT RX USA 2 mg, 20-270 tablets
TIZANIDINE STAT RX USA 2 mg, 28-140 tablets
TIZANIDINE STAT RX USA 4 mg, 15-270 tablets
TIZANIDINE STAT RX USA 4 mg, 28-140 tablets
TIZANIDINE UDL 4 mg, 100 tablets
TIZANIDINE UNICHEM 2 mg, 150 tablets
TIZANIDINE UNICHEM 4 mg, 150 tablets
TIZANIDINE UNIT DOSE SERVICES 2 mg, 30, 60 and 90 tablets
TIZANIDINE UNIT DOSE SERVICES 4 mg, 30-120 tablets
TIZANIDINE WATSON 2 mg, 150 capsules
TIZANIDINE WATSON 4 mg, 150 capsules
TIZANIDINE WATSON 6 mg, 150 capsules
ZANAFLEX 2 mg, 90 and 150 capsules
ZANAFLEX 4 mg, 10-150 capsules
ZANAFLEX 4 mg, 150 tablets
ZANAFLEX 6 mg, 30, 60, 90 and 150 capsules
Page updated: December 11, 2010.